Rapid Synthesis of the Ervitsine Alkaloid Skeleton by a Sequential RCM-Heck Cyclization Approach
An efficient approach to the bridged framework of the indole alkaloid ervitsine, featuring a ring-closing metathesis reaction from a 2,3-disubstituted indole followed by a vinyl halide Heck cyclization upon the resulting cycloheptene ring, is described.
| Autores: | , , , |
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| Tipo de documento: | artigo |
| Estado: | Versión aceptada para publicación |
| Data de publicação: | 2008 |
| País: | España |
| Recursos: | Universidad de Barcelona |
| Repositório: | Dipòsit Digital de la UB |
| OAI Identifier: | oai:diposit.ub.edu:2445/161251 |
| Acesso em linha: | https://hdl.handle.net/2445/161251 |
| Access Level: | Acceso aberto |
| Palavra-chave: | Síntesi orgànica Metàtesi (Química) Alcaloides Organic synthesis Metathesis (Chemistry) Alkaloids |
| Resumo: | An efficient approach to the bridged framework of the indole alkaloid ervitsine, featuring a ring-closing metathesis reaction from a 2,3-disubstituted indole followed by a vinyl halide Heck cyclization upon the resulting cycloheptene ring, is described. |
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