Laser-driven radiation sources for in vitro radiobiological studies
Laser-driven radiation sources have emerged as a compact and promising alternative to conventional large-scale accelerators for radiobiological research. However, their application in this field remains challenging due to limitations in dose control, reproducibility, and beam stability. This thesis...
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| Tipo de recurso: | tesis doctoral |
| Fecha de publicación: | 2026 |
| País: | España |
| Institución: | Universidad de Santiago de Compostela (USC) |
| Repositorio: | Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela |
| Idioma: | inglés |
| OAI Identifier: | oai:dnet:minerva_____::869cd0eb2d807cc972fd16b3b9059988 |
| Acceso en línea: | https://hdl.handle.net/10347/47565 |
| Access Level: | acceso abierto |
| Palabra clave: | radiobiology laser acceleration cell 240606 Física médica 220910 Láseres |
| Sumario: | Laser-driven radiation sources have emerged as a compact and promising alternative to conventional large-scale accelerators for radiobiological research. However, their application in this field remains challenging due to limitations in dose control, reproducibility, and beam stability. This thesis investigates the feasibility of employing laser-driven radiation sources for in vitro radiobiological studies, with a particular emphasis on the validation of irradiation experiments performed at high repetition rates. Two independent experimental setups were designed, commissioned, and validated to enable multi-shot irradiation of human lung adenocarcinoma cell cultures using laser-driven x-rays and protons. |
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