Transient platelet hyporesponsiveness in non-ischemic arrhythmogenic cardiac arrest after achieving restoration of spontaneous circulation in pigs.

This study shows that variable and often attenuated platelet reactivity after CA, together with neutral OHCA outcome data argues against indiscriminate antiplatelet loading before the cause of shock is clarified. For ambiguous prehospital cardiogenic shock, initial management should prioritize early...

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Detalles Bibliográficos
Autores: Magaldi, Marta, Giron, Gabriela O., Radike, Monika, Ramos-Regalado, Lisaidy, Alcover, Sebastia, Otero, Sergi, Catalina, Pablo, Canovas, Maria Angeles, Vendrell, Marina, Dantas, Ana Paula, Gorog, Diana Adrienne, Padro, Teresa, Borrell, Maria, Badimon, Lina, Peray Bruel, Claudia de, Vilahur, Gemma
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2026
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/227496
Acceso en línea:https://hdl.handle.net/2445/227496
Access Level:acceso embargado
Palabra clave:Trombosi
Aturada cardíaca
Thrombosis
Cardiac arrest
Descripción
Sumario:This study shows that variable and often attenuated platelet reactivity after CA, together with neutral OHCA outcome data argues against indiscriminate antiplatelet loading before the cause of shock is clarified. For ambiguous prehospital cardiogenic shock, initial management should prioritize early coronary angiography and comprehensive shock care, reserving full antiplatelet loading for those in whom AMI is confirmed or strongly suspected per local protocols.

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