Stereospecific SN2@P reactions: Novel access to bulky P-stereogenic ligands

The stereospecific hydrolysis of bulky aminophosphine boranes is reported for the first time. The resulting phosphinous acid boranes, upon activation, undergo stereospecific nucleophilic substitution reaction at the phosphorous center with amine nucleophiles. The combination of these two processes p...

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Detalles Bibliográficos
Autores: Orgué Gassol, Sílvia, Flores-Gaspar, Areli, Biosca, Maria, Pàmies, Oscar, Diéguez, Montserrat, Riera i Escalé, Antoni, Verdaguer i Espaulella, Xavier
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/68334
Acceso en línea:https://hdl.handle.net/2445/68334
Access Level:acceso abierto
Palabra clave:Hidròlisi
Lligands
Catàlisi asimètrica
Compostos de bor
Hydrolysis
Ligands
Enantioselective catalysis
Boron compounds
Descripción
Sumario:The stereospecific hydrolysis of bulky aminophosphine boranes is reported for the first time. The resulting phosphinous acid boranes, upon activation, undergo stereospecific nucleophilic substitution reaction at the phosphorous center with amine nucleophiles. The combination of these two processes provides a novel access to bulky P*-ligands.