Pepsin egg white hydrolysate ameliorates metabolic syndrome in high-fat/high-dextrose fed rats.
The aim of this study was to examine the effect of a pepsin egg white hydrolysate (EWH) on metabolic complications using a high-fat/high-dextrose diet-induced Metabolic Syndrome (MetS) experimental model. Male Wistar rats where divided in 4 groups which received: standard diet and water (C), standar...
| Autores: | , , , , , , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 2018 |
| País: | España |
| Institución: | Universidad Rey Juan Carlos |
| Repositorio: | BURJC-Digital. Repositorio Institucional de la Universidad Rey Juan Carlos |
| OAI Identifier: | oai:burjcdigital.urjc.es:10115/32308 |
| Acceso en línea: | https://hdl.handle.net/10115/32308 |
| Access Level: | acceso abierto |
| Palabra clave: | Egg white hydrolysate bioactive peptides metabolic syndrome diet induced obesity rat model |
| Sumario: | The aim of this study was to examine the effect of a pepsin egg white hydrolysate (EWH) on metabolic complications using a high-fat/high-dextrose diet-induced Metabolic Syndrome (MetS) experimental model. Male Wistar rats where divided in 4 groups which received: standard diet and water (C), standard diet and a solution with 1g/kg/day of EWH (CH), high-fat/high-dextrose diet and water (MS), and high-fat/high-dextrose diet and a solution with 1g/kg/day of EWH (MSH). EWH consumption normalized body weight gain, the abdominal obesity and the peripheral neuropathy developed in MetS animals, reduced adipose tissue and liver weight, as well as plasma glucose. Oxidative stress and inflammation biomarkers were normalized in MSH animals. In conclusion oral administration of EWH could be used as a functional food ingredient to improve some complications associated to MetS induced by unhealthy diets |
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