Raw data of dots and whiskers graphic, used in the manuscript: Targeting aggressive von Hippel Lindau Disease with a germinal mutation in the CHEK2 gene [DATASET]
Data are expressed as means ± standard deviation (SD) and each experiment was repeated at least 3 times. Statistical analyses were performed using Student’s t-test for comparisons between two groups and two-way ANOVA followed by Tukey’s multiple comparisons test for analyses involving two independen...
| Autores: | , , , , , , , , |
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| Tipo de recurso: | conjunto de datos |
| Fecha de publicación: | 2025 |
| País: | España |
| Institución: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/404355 |
| Acceso en línea: | http://hdl.handle.net/10261/404355 https://doi.org/10.20350/digitalCSIC/17674 |
| Access Level: | acceso abierto |
| Palabra clave: | von Hippel-Lindau Hemangioblastoma ccRCC Adrenergic receptor CHEK2 ICI- 118,551 Olaparib Personalized medicine |
| Sumario: | Data are expressed as means ± standard deviation (SD) and each experiment was repeated at least 3 times. Statistical analyses were performed using Student’s t-test for comparisons between two groups and two-way ANOVA followed by Tukey’s multiple comparisons test for analyses involving two independent variables (performed using GraphPad Prism version 8.0.1). The normality and homogeneity of variances were verified before applying parametric tests. Differences were considered statistically significant at p < 0.05, with significance levels indicated as follows: p < 0.05, p < 0.01, p < 0.001, and p < 0.0001. RT-qPCR and Western Blot Fig 3B, S1, and the commercial CellTiter Glo Luminescent Cell Viability Assay kit (Promega) for Fig4B and S2. Relationship between files, if important: raw data for Fig 3A and S1 on dots_whiskers.xls and qPCR.xls; raw data for Fig 4B and S2 on HUVECs_HB viability-ICI-OLA_2025.xls |
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