Lipidomic characterization of the milk fat globule membrane polar lipids

The milk fat globule structure is of colloidal nature with a triacylglycerol (TAG) rich core surrounded by the milk fat globule membrane (MFGM), emulsified and dispersed into the aqueous phase. MFGM is a unique trilayer structure, with the inner monolayer stemming from the endoplasmic reticulum and...

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Detalles Bibliográficos
Autores: Montero, Olimpio, Fontecha, F. Javier, Castro-Gómez, Pilar, Rodríguez Alcalá, Luis M.
Tipo de recurso: otro
Estado:Versión aceptada para publicación
Fecha de publicación:2020
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/228905
Acceso en línea:http://hdl.handle.net/10261/228905
Access Level:acceso abierto
Descripción
Sumario:The milk fat globule structure is of colloidal nature with a triacylglycerol (TAG) rich core surrounded by the milk fat globule membrane (MFGM), emulsified and dispersed into the aqueous phase. MFGM is a unique trilayer structure, with the inner monolayer stemming from the endoplasmic reticulum and the outer bilayer from the apical cells of the mammary gland. Therefore, as biological membrane, MFGM is a highly complex ensemble of self-associating lipids, mainly phospholipids (PL), into which a diverse array of proteins and other biomolecules are embedded. Although PL constitute a small percentage of the milk total lipids (0.5–2% in cow’s milk), they may represent a substantial part of the total lipids in buttermilk, the aqueous phase released during the elaboration of butter, owing to the presence of significant quantities of MFGM components in this by-product.