Cutaneous leishmaniasis in two horses

This report contains the clinical, histologic, immunohistochemical, and electron microscopic findings in two cases of equine cutaneous leishmaniasis. Nodular, sometimes crusty or ulcerated lesions were confined to the pinna and adjacent neck in both animals. The dermal inflammatory infiltrate was ly...

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Bibliographic Details
Authors: Ramos Vara, José Antonio, Ortiz-Santiago, B., Segalés Coma, Joaquim|||0000-0002-1539-7261, Dunstan, R. W.
Format: article
Publication Date:1996
Country:España
Institution:Universitat Autònoma de Barcelona
Repository:Dipòsit Digital de Documents de la UAB
Language:English
OAI Identifier:oai:ddd.uab.cat:307594
Online Access:https://ddd.uab.cat/record/307594
https://dx.doi.org/urn:doi:10.1177/030098589603300619
Access Level:Open access
Keyword:Electron microscopy
Histopathology
Horses
Immunohistochemistry
Leishmaniasis
Skin
Description
Summary:This report contains the clinical, histologic, immunohistochemical, and electron microscopic findings in two cases of equine cutaneous leishmaniasis. Nodular, sometimes crusty or ulcerated lesions were confined to the pinna and adjacent neck in both animals. The dermal inflammatory infiltrate was lymphohistiocytic in horse No. 1 and pyogranulomatous with formation of tuberculoid granulomas in horse No. 2. Numerous Leishmania organisms were found within macrophages in both animals. There was moderate to intense and specific reaction by immunoperoxidase using a polyclonal antiserum against Leishmania in both horses. Leishmania amastigotes were also revealed by electron microscopy. This is the first report of equine cutaneous leishmaniasis recognized in North America and Puerto Rico. Leishmaniasis should be considered in the differential diagnosis of cutaneous nodular diseases in the horse.