Cutaneous leishmaniasis in two horses

This report contains the clinical, histologic, immunohistochemical, and electron microscopic findings in two cases of equine cutaneous leishmaniasis. Nodular, sometimes crusty or ulcerated lesions were confined to the pinna and adjacent neck in both animals. The dermal inflammatory infiltrate was ly...

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Detalles Bibliográficos
Autores: Ramos Vara, José Antonio, Ortiz-Santiago, B., Segalés Coma, Joaquim|||0000-0002-1539-7261, Dunstan, R. W.
Tipo de recurso: artículo
Fecha de publicación:1996
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:307594
Acceso en línea:https://ddd.uab.cat/record/307594
https://dx.doi.org/urn:doi:10.1177/030098589603300619
Access Level:acceso abierto
Palabra clave:Electron microscopy
Histopathology
Horses
Immunohistochemistry
Leishmaniasis
Skin
Descripción
Sumario:This report contains the clinical, histologic, immunohistochemical, and electron microscopic findings in two cases of equine cutaneous leishmaniasis. Nodular, sometimes crusty or ulcerated lesions were confined to the pinna and adjacent neck in both animals. The dermal inflammatory infiltrate was lymphohistiocytic in horse No. 1 and pyogranulomatous with formation of tuberculoid granulomas in horse No. 2. Numerous Leishmania organisms were found within macrophages in both animals. There was moderate to intense and specific reaction by immunoperoxidase using a polyclonal antiserum against Leishmania in both horses. Leishmania amastigotes were also revealed by electron microscopy. This is the first report of equine cutaneous leishmaniasis recognized in North America and Puerto Rico. Leishmaniasis should be considered in the differential diagnosis of cutaneous nodular diseases in the horse.