CyEnGNet—App: A new Cytoscape app for the reconstruction of large co-expression networks using an ensemble approach

The construction of gene co-expression networks is an essential tool in Bioinformatics for discovering useful biological knowledge. There are a multitude of methodologies related to the construction of this type of network, and one of them is EnGNet, which carries out a joint and greedy approach to...

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Detalles Bibliográficos
Autores: Del Saz Navarro, Dulcenombre de María, López Fernández, Aurelio, Gómez-Vela, Francisco Antonio, Rodríguez Baena, Domingo Savio
Tipo de recurso: artículo
Fecha de publicación:2024
País:España
Institución:Universidad Pablo de Olavide (UPO)
Repositorio:RIO. Repositorio Institucional Olavide
Idioma:inglés
OAI Identifier:oai:rio.upo.es:10433/22427
Acceso en línea:https://hdl.handle.net/10433/22427
Access Level:acceso abierto
Palabra clave:Bioinformatics
Cytoscape
Gene Network
Network analysis
Visualisation
Descripción
Sumario:The construction of gene co-expression networks is an essential tool in Bioinformatics for discovering useful biological knowledge. There are a multitude of methodologies related to the construction of this type of network, and one of them is EnGNet, which carries out a joint and greedy approach to the reconstruction of large gene coexpression networks. This work introduces CyEnGNet-App, a Cytoscape application designed to integrate and leverage the EnGNet algorithm. The application allows dynamic interaction and visualisation of gene networks and integration with other Cytoscape applications. CyEnGNet-App is a valuable addition to the field of Bioinformatics, improving the reconstruction of genetic networks and providing a more accessible and efficient user experience in Cytoscape.