Diagnosis, treatment, and response assessment in solitary plasmacytoma: updated recommendations from a European Expert Panel

Solitary plasmacytoma is an infrequent form of plasma cell dyscrasia that presents as a single mass of monoclonal plasma cells, located either extramedullary or intraosseous. In some patients, a bone marrow aspiration can detect a low monoclonal plasma cell infiltration which indicates a high risk o...

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Autores: Caers, J. (Jo)|||/items/403726c8-4135-42b4-995f-a3173e1e6e4a, Paiva, B. (Bruno)|||/items/b2c3efc5-27e1-4425-b452-efba1522c1d5, Zamagni, E. (Elena)|||/items/3ed4ddd1-d487-41a8-ab7e-f23ebfbd71e4, Leleu, X. (Xavier)|||/items/aae83612-eb31-463f-b7e2-59e5d13fc75a, Bladé, J. (Joan)|||/items/2e3393a4-11c5-4a58-8b64-52150839a266, Kristinsson, S.Y. (S. Y.)|||/items/c7617c3b-deff-40c6-a0be-5a9228b0a1b7, Touzeau, C. (C.)|||/items/859cd94f-84a8-48fe-9da0-00046e5341f1, Abildgaard, N. (N.)|||/items/35ad69ff-df3f-475d-95bd-4375f995dbdf, Terpos, E. (Evangelos)|||/items/f7dbaa50-9ab3-42ba-bf5a-d80977a9f8d4, Heusschen, R. (R.)|||/items/4ea8a18c-7f2f-4a30-84a6-2bc146a95b9c, Ocio, E.M. (Enrique M.)|||/items/2e2c579b-5c69-4327-bbef-0107e8ab4f2e, Delforge, M. (Michel)|||/items/f642fb6d-d632-430b-9601-260fd0bf5b45, Sezer, O. (O.)|||/items/ca2ab2ab-f3b3-499f-8b6b-c77552a7ef04, Beksac, M. (Meral)|||/items/705a45fb-336b-4552-ab63-514429511250, Ludwig, H. (Heinz)|||/items/4626d464-635c-4aac-bffe-d9eeef1e4380, Merlini, G. (G.)|||/items/812d1f01-e28b-456a-952a-0a4e3937e446, Moreau, P. (Philippe)|||/items/3d8d9f42-9629-4e12-9854-43031d9b6332, Zweegman, S. (Sonja)|||/items/e3037369-fb2d-4527-bd35-f49dbd8ab08b, Engelhardt, M. (Monika)|||/items/19022ea7-5d61-41b2-8552-38296d8afb2c, Rosiñol, L. (Laura)|||/items/60f5826d-b5d8-4972-b968-ccda26113fbf
Tipo de recurso: artículo
Fecha de publicación:2018
País:España
Institución:Universidad de Navarra
Repositorio:Dadun. Depósito Académico Digital de la Universidad de Navarra
Idioma:inglés
OAI Identifier:oai:dadun.unav.edu:10171/65654
Acceso en línea:https://hdl.handle.net/10171/65654
Access Level:acceso abierto
Palabra clave:Solitary plasmacytoma
Extramedullary plasmacytoma
Myeloma
Plasma cell dyscrasia
PET/CT
MRI
Radiotherapy
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spelling Diagnosis, treatment, and response assessment in solitary plasmacytoma: updated recommendations from a European Expert PanelCaers, J. (Jo)|||/items/403726c8-4135-42b4-995f-a3173e1e6e4aPaiva, B. (Bruno)|||/items/b2c3efc5-27e1-4425-b452-efba1522c1d5Zamagni, E. (Elena)|||/items/3ed4ddd1-d487-41a8-ab7e-f23ebfbd71e4Leleu, X. (Xavier)|||/items/aae83612-eb31-463f-b7e2-59e5d13fc75aBladé, J. (Joan)|||/items/2e3393a4-11c5-4a58-8b64-52150839a266Kristinsson, S.Y. (S. Y.)|||/items/c7617c3b-deff-40c6-a0be-5a9228b0a1b7Touzeau, C. (C.)|||/items/859cd94f-84a8-48fe-9da0-00046e5341f1Abildgaard, N. (N.)|||/items/35ad69ff-df3f-475d-95bd-4375f995dbdfTerpos, E. (Evangelos)|||/items/f7dbaa50-9ab3-42ba-bf5a-d80977a9f8d4Heusschen, R. (R.)|||/items/4ea8a18c-7f2f-4a30-84a6-2bc146a95b9cOcio, E.M. (Enrique M.)|||/items/2e2c579b-5c69-4327-bbef-0107e8ab4f2eDelforge, M. (Michel)|||/items/f642fb6d-d632-430b-9601-260fd0bf5b45Sezer, O. (O.)|||/items/ca2ab2ab-f3b3-499f-8b6b-c77552a7ef04Beksac, M. (Meral)|||/items/705a45fb-336b-4552-ab63-514429511250Ludwig, H. (Heinz)|||/items/4626d464-635c-4aac-bffe-d9eeef1e4380Merlini, G. (G.)|||/items/812d1f01-e28b-456a-952a-0a4e3937e446Moreau, P. (Philippe)|||/items/3d8d9f42-9629-4e12-9854-43031d9b6332Zweegman, S. (Sonja)|||/items/e3037369-fb2d-4527-bd35-f49dbd8ab08bEngelhardt, M. (Monika)|||/items/19022ea7-5d61-41b2-8552-38296d8afb2cRosiñol, L. (Laura)|||/items/60f5826d-b5d8-4972-b968-ccda26113fbfSolitary plasmacytomaExtramedullary plasmacytomaMyelomaPlasma cell dyscrasiaPET/CTMRIRadiotherapySolitary plasmacytoma is an infrequent form of plasma cell dyscrasia that presents as a single mass of monoclonal plasma cells, located either extramedullary or intraosseous. In some patients, a bone marrow aspiration can detect a low monoclonal plasma cell infiltration which indicates a high risk of early progression to an overt myeloma disease. Before treatment initiation, whole body positron emission tomography–computed tomography or magnetic resonance imaging should be performed to exclude the presence of additional malignant lesions. For decades, treatment has been based on high-dose radiation, but studies exploring the potential benefit of systemic therapies for high-risk patients are urgently needed. In this review, a panel of expert European hematologists updates the recommendations on the diagnosis and management of patients with solitary plasmacytoma.BioMed CentralDadun. Depósito Académico Digital Universidad de Navarra20232023-03-0920182018-01-0120182018-01-01journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10171/65654reponame:Dadun. Depósito Académico Digital de la Universidad de Navarrainstname:Universidad de NavarraInglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:dadun.unav.edu:10171/656542026-06-21T12:47:57Z
dc.title.none.fl_str_mv Diagnosis, treatment, and response assessment in solitary plasmacytoma: updated recommendations from a European Expert Panel
title Diagnosis, treatment, and response assessment in solitary plasmacytoma: updated recommendations from a European Expert Panel
spellingShingle Diagnosis, treatment, and response assessment in solitary plasmacytoma: updated recommendations from a European Expert Panel
Caers, J. (Jo)|||/items/403726c8-4135-42b4-995f-a3173e1e6e4a
Solitary plasmacytoma
Extramedullary plasmacytoma
Myeloma
Plasma cell dyscrasia
PET/CT
MRI
Radiotherapy
title_short Diagnosis, treatment, and response assessment in solitary plasmacytoma: updated recommendations from a European Expert Panel
title_full Diagnosis, treatment, and response assessment in solitary plasmacytoma: updated recommendations from a European Expert Panel
title_fullStr Diagnosis, treatment, and response assessment in solitary plasmacytoma: updated recommendations from a European Expert Panel
title_full_unstemmed Diagnosis, treatment, and response assessment in solitary plasmacytoma: updated recommendations from a European Expert Panel
title_sort Diagnosis, treatment, and response assessment in solitary plasmacytoma: updated recommendations from a European Expert Panel
dc.creator.none.fl_str_mv Caers, J. (Jo)|||/items/403726c8-4135-42b4-995f-a3173e1e6e4a
Paiva, B. (Bruno)|||/items/b2c3efc5-27e1-4425-b452-efba1522c1d5
Zamagni, E. (Elena)|||/items/3ed4ddd1-d487-41a8-ab7e-f23ebfbd71e4
Leleu, X. (Xavier)|||/items/aae83612-eb31-463f-b7e2-59e5d13fc75a
Bladé, J. (Joan)|||/items/2e3393a4-11c5-4a58-8b64-52150839a266
Kristinsson, S.Y. (S. Y.)|||/items/c7617c3b-deff-40c6-a0be-5a9228b0a1b7
Touzeau, C. (C.)|||/items/859cd94f-84a8-48fe-9da0-00046e5341f1
Abildgaard, N. (N.)|||/items/35ad69ff-df3f-475d-95bd-4375f995dbdf
Terpos, E. (Evangelos)|||/items/f7dbaa50-9ab3-42ba-bf5a-d80977a9f8d4
Heusschen, R. (R.)|||/items/4ea8a18c-7f2f-4a30-84a6-2bc146a95b9c
Ocio, E.M. (Enrique M.)|||/items/2e2c579b-5c69-4327-bbef-0107e8ab4f2e
Delforge, M. (Michel)|||/items/f642fb6d-d632-430b-9601-260fd0bf5b45
Sezer, O. (O.)|||/items/ca2ab2ab-f3b3-499f-8b6b-c77552a7ef04
Beksac, M. (Meral)|||/items/705a45fb-336b-4552-ab63-514429511250
Ludwig, H. (Heinz)|||/items/4626d464-635c-4aac-bffe-d9eeef1e4380
Merlini, G. (G.)|||/items/812d1f01-e28b-456a-952a-0a4e3937e446
Moreau, P. (Philippe)|||/items/3d8d9f42-9629-4e12-9854-43031d9b6332
Zweegman, S. (Sonja)|||/items/e3037369-fb2d-4527-bd35-f49dbd8ab08b
Engelhardt, M. (Monika)|||/items/19022ea7-5d61-41b2-8552-38296d8afb2c
Rosiñol, L. (Laura)|||/items/60f5826d-b5d8-4972-b968-ccda26113fbf
author Caers, J. (Jo)|||/items/403726c8-4135-42b4-995f-a3173e1e6e4a
author_facet Caers, J. (Jo)|||/items/403726c8-4135-42b4-995f-a3173e1e6e4a
Paiva, B. (Bruno)|||/items/b2c3efc5-27e1-4425-b452-efba1522c1d5
Zamagni, E. (Elena)|||/items/3ed4ddd1-d487-41a8-ab7e-f23ebfbd71e4
Leleu, X. (Xavier)|||/items/aae83612-eb31-463f-b7e2-59e5d13fc75a
Bladé, J. (Joan)|||/items/2e3393a4-11c5-4a58-8b64-52150839a266
Kristinsson, S.Y. (S. Y.)|||/items/c7617c3b-deff-40c6-a0be-5a9228b0a1b7
Touzeau, C. (C.)|||/items/859cd94f-84a8-48fe-9da0-00046e5341f1
Abildgaard, N. (N.)|||/items/35ad69ff-df3f-475d-95bd-4375f995dbdf
Terpos, E. (Evangelos)|||/items/f7dbaa50-9ab3-42ba-bf5a-d80977a9f8d4
Heusschen, R. (R.)|||/items/4ea8a18c-7f2f-4a30-84a6-2bc146a95b9c
Ocio, E.M. (Enrique M.)|||/items/2e2c579b-5c69-4327-bbef-0107e8ab4f2e
Delforge, M. (Michel)|||/items/f642fb6d-d632-430b-9601-260fd0bf5b45
Sezer, O. (O.)|||/items/ca2ab2ab-f3b3-499f-8b6b-c77552a7ef04
Beksac, M. (Meral)|||/items/705a45fb-336b-4552-ab63-514429511250
Ludwig, H. (Heinz)|||/items/4626d464-635c-4aac-bffe-d9eeef1e4380
Merlini, G. (G.)|||/items/812d1f01-e28b-456a-952a-0a4e3937e446
Moreau, P. (Philippe)|||/items/3d8d9f42-9629-4e12-9854-43031d9b6332
Zweegman, S. (Sonja)|||/items/e3037369-fb2d-4527-bd35-f49dbd8ab08b
Engelhardt, M. (Monika)|||/items/19022ea7-5d61-41b2-8552-38296d8afb2c
Rosiñol, L. (Laura)|||/items/60f5826d-b5d8-4972-b968-ccda26113fbf
author_role author
author2 Paiva, B. (Bruno)|||/items/b2c3efc5-27e1-4425-b452-efba1522c1d5
Zamagni, E. (Elena)|||/items/3ed4ddd1-d487-41a8-ab7e-f23ebfbd71e4
Leleu, X. (Xavier)|||/items/aae83612-eb31-463f-b7e2-59e5d13fc75a
Bladé, J. (Joan)|||/items/2e3393a4-11c5-4a58-8b64-52150839a266
Kristinsson, S.Y. (S. Y.)|||/items/c7617c3b-deff-40c6-a0be-5a9228b0a1b7
Touzeau, C. (C.)|||/items/859cd94f-84a8-48fe-9da0-00046e5341f1
Abildgaard, N. (N.)|||/items/35ad69ff-df3f-475d-95bd-4375f995dbdf
Terpos, E. (Evangelos)|||/items/f7dbaa50-9ab3-42ba-bf5a-d80977a9f8d4
Heusschen, R. (R.)|||/items/4ea8a18c-7f2f-4a30-84a6-2bc146a95b9c
Ocio, E.M. (Enrique M.)|||/items/2e2c579b-5c69-4327-bbef-0107e8ab4f2e
Delforge, M. (Michel)|||/items/f642fb6d-d632-430b-9601-260fd0bf5b45
Sezer, O. (O.)|||/items/ca2ab2ab-f3b3-499f-8b6b-c77552a7ef04
Beksac, M. (Meral)|||/items/705a45fb-336b-4552-ab63-514429511250
Ludwig, H. (Heinz)|||/items/4626d464-635c-4aac-bffe-d9eeef1e4380
Merlini, G. (G.)|||/items/812d1f01-e28b-456a-952a-0a4e3937e446
Moreau, P. (Philippe)|||/items/3d8d9f42-9629-4e12-9854-43031d9b6332
Zweegman, S. (Sonja)|||/items/e3037369-fb2d-4527-bd35-f49dbd8ab08b
Engelhardt, M. (Monika)|||/items/19022ea7-5d61-41b2-8552-38296d8afb2c
Rosiñol, L. (Laura)|||/items/60f5826d-b5d8-4972-b968-ccda26113fbf
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dc.contributor.none.fl_str_mv Dadun. Depósito Académico Digital Universidad de Navarra
dc.subject.none.fl_str_mv Solitary plasmacytoma
Extramedullary plasmacytoma
Myeloma
Plasma cell dyscrasia
PET/CT
MRI
Radiotherapy
topic Solitary plasmacytoma
Extramedullary plasmacytoma
Myeloma
Plasma cell dyscrasia
PET/CT
MRI
Radiotherapy
description Solitary plasmacytoma is an infrequent form of plasma cell dyscrasia that presents as a single mass of monoclonal plasma cells, located either extramedullary or intraosseous. In some patients, a bone marrow aspiration can detect a low monoclonal plasma cell infiltration which indicates a high risk of early progression to an overt myeloma disease. Before treatment initiation, whole body positron emission tomography–computed tomography or magnetic resonance imaging should be performed to exclude the presence of additional malignant lesions. For decades, treatment has been based on high-dose radiation, but studies exploring the potential benefit of systemic therapies for high-risk patients are urgently needed. In this review, a panel of expert European hematologists updates the recommendations on the diagnosis and management of patients with solitary plasmacytoma.
publishDate 2018
dc.date.none.fl_str_mv 2018
2018-01-01
2018
2018-01-01
2023
2023-03-09
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/10171/65654
url https://hdl.handle.net/10171/65654
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:Dadun. Depósito Académico Digital de la Universidad de Navarra
instname:Universidad de Navarra
instname_str Universidad de Navarra
reponame_str Dadun. Depósito Académico Digital de la Universidad de Navarra
collection Dadun. Depósito Académico Digital de la Universidad de Navarra
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