Diagnosis, treatment, and response assessment in solitary plasmacytoma: updated recommendations from a European Expert Panel
Solitary plasmacytoma is an infrequent form of plasma cell dyscrasia that presents as a single mass of monoclonal plasma cells, located either extramedullary or intraosseous. In some patients, a bone marrow aspiration can detect a low monoclonal plasma cell infiltration which indicates a high risk o...
| Autores: | , , , , , , , , , , , , , , , , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Fecha de publicación: | 2018 |
| País: | España |
| Institución: | Universidad de Navarra |
| Repositorio: | Dadun. Depósito Académico Digital de la Universidad de Navarra |
| Idioma: | inglés |
| OAI Identifier: | oai:dadun.unav.edu:10171/65654 |
| Acceso en línea: | https://hdl.handle.net/10171/65654 |
| Access Level: | acceso abierto |
| Palabra clave: | Solitary plasmacytoma Extramedullary plasmacytoma Myeloma Plasma cell dyscrasia PET/CT MRI Radiotherapy |
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Diagnosis, treatment, and response assessment in solitary plasmacytoma: updated recommendations from a European Expert PanelCaers, J. (Jo)|||/items/403726c8-4135-42b4-995f-a3173e1e6e4aPaiva, B. (Bruno)|||/items/b2c3efc5-27e1-4425-b452-efba1522c1d5Zamagni, E. (Elena)|||/items/3ed4ddd1-d487-41a8-ab7e-f23ebfbd71e4Leleu, X. (Xavier)|||/items/aae83612-eb31-463f-b7e2-59e5d13fc75aBladé, J. (Joan)|||/items/2e3393a4-11c5-4a58-8b64-52150839a266Kristinsson, S.Y. (S. Y.)|||/items/c7617c3b-deff-40c6-a0be-5a9228b0a1b7Touzeau, C. (C.)|||/items/859cd94f-84a8-48fe-9da0-00046e5341f1Abildgaard, N. (N.)|||/items/35ad69ff-df3f-475d-95bd-4375f995dbdfTerpos, E. (Evangelos)|||/items/f7dbaa50-9ab3-42ba-bf5a-d80977a9f8d4Heusschen, R. (R.)|||/items/4ea8a18c-7f2f-4a30-84a6-2bc146a95b9cOcio, E.M. (Enrique M.)|||/items/2e2c579b-5c69-4327-bbef-0107e8ab4f2eDelforge, M. (Michel)|||/items/f642fb6d-d632-430b-9601-260fd0bf5b45Sezer, O. (O.)|||/items/ca2ab2ab-f3b3-499f-8b6b-c77552a7ef04Beksac, M. (Meral)|||/items/705a45fb-336b-4552-ab63-514429511250Ludwig, H. (Heinz)|||/items/4626d464-635c-4aac-bffe-d9eeef1e4380Merlini, G. (G.)|||/items/812d1f01-e28b-456a-952a-0a4e3937e446Moreau, P. (Philippe)|||/items/3d8d9f42-9629-4e12-9854-43031d9b6332Zweegman, S. (Sonja)|||/items/e3037369-fb2d-4527-bd35-f49dbd8ab08bEngelhardt, M. (Monika)|||/items/19022ea7-5d61-41b2-8552-38296d8afb2cRosiñol, L. (Laura)|||/items/60f5826d-b5d8-4972-b968-ccda26113fbfSolitary plasmacytomaExtramedullary plasmacytomaMyelomaPlasma cell dyscrasiaPET/CTMRIRadiotherapySolitary plasmacytoma is an infrequent form of plasma cell dyscrasia that presents as a single mass of monoclonal plasma cells, located either extramedullary or intraosseous. In some patients, a bone marrow aspiration can detect a low monoclonal plasma cell infiltration which indicates a high risk of early progression to an overt myeloma disease. Before treatment initiation, whole body positron emission tomography–computed tomography or magnetic resonance imaging should be performed to exclude the presence of additional malignant lesions. For decades, treatment has been based on high-dose radiation, but studies exploring the potential benefit of systemic therapies for high-risk patients are urgently needed. In this review, a panel of expert European hematologists updates the recommendations on the diagnosis and management of patients with solitary plasmacytoma.BioMed CentralDadun. Depósito Académico Digital Universidad de Navarra20232023-03-0920182018-01-0120182018-01-01journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10171/65654reponame:Dadun. Depósito Académico Digital de la Universidad de Navarrainstname:Universidad de NavarraInglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:dadun.unav.edu:10171/656542026-06-21T12:47:57Z |
| dc.title.none.fl_str_mv |
Diagnosis, treatment, and response assessment in solitary plasmacytoma: updated recommendations from a European Expert Panel |
| title |
Diagnosis, treatment, and response assessment in solitary plasmacytoma: updated recommendations from a European Expert Panel |
| spellingShingle |
Diagnosis, treatment, and response assessment in solitary plasmacytoma: updated recommendations from a European Expert Panel Caers, J. (Jo)|||/items/403726c8-4135-42b4-995f-a3173e1e6e4a Solitary plasmacytoma Extramedullary plasmacytoma Myeloma Plasma cell dyscrasia PET/CT MRI Radiotherapy |
| title_short |
Diagnosis, treatment, and response assessment in solitary plasmacytoma: updated recommendations from a European Expert Panel |
| title_full |
Diagnosis, treatment, and response assessment in solitary plasmacytoma: updated recommendations from a European Expert Panel |
| title_fullStr |
Diagnosis, treatment, and response assessment in solitary plasmacytoma: updated recommendations from a European Expert Panel |
| title_full_unstemmed |
Diagnosis, treatment, and response assessment in solitary plasmacytoma: updated recommendations from a European Expert Panel |
| title_sort |
Diagnosis, treatment, and response assessment in solitary plasmacytoma: updated recommendations from a European Expert Panel |
| dc.creator.none.fl_str_mv |
Caers, J. (Jo)|||/items/403726c8-4135-42b4-995f-a3173e1e6e4a Paiva, B. (Bruno)|||/items/b2c3efc5-27e1-4425-b452-efba1522c1d5 Zamagni, E. (Elena)|||/items/3ed4ddd1-d487-41a8-ab7e-f23ebfbd71e4 Leleu, X. (Xavier)|||/items/aae83612-eb31-463f-b7e2-59e5d13fc75a Bladé, J. (Joan)|||/items/2e3393a4-11c5-4a58-8b64-52150839a266 Kristinsson, S.Y. (S. Y.)|||/items/c7617c3b-deff-40c6-a0be-5a9228b0a1b7 Touzeau, C. (C.)|||/items/859cd94f-84a8-48fe-9da0-00046e5341f1 Abildgaard, N. (N.)|||/items/35ad69ff-df3f-475d-95bd-4375f995dbdf Terpos, E. (Evangelos)|||/items/f7dbaa50-9ab3-42ba-bf5a-d80977a9f8d4 Heusschen, R. (R.)|||/items/4ea8a18c-7f2f-4a30-84a6-2bc146a95b9c Ocio, E.M. (Enrique M.)|||/items/2e2c579b-5c69-4327-bbef-0107e8ab4f2e Delforge, M. (Michel)|||/items/f642fb6d-d632-430b-9601-260fd0bf5b45 Sezer, O. (O.)|||/items/ca2ab2ab-f3b3-499f-8b6b-c77552a7ef04 Beksac, M. (Meral)|||/items/705a45fb-336b-4552-ab63-514429511250 Ludwig, H. (Heinz)|||/items/4626d464-635c-4aac-bffe-d9eeef1e4380 Merlini, G. (G.)|||/items/812d1f01-e28b-456a-952a-0a4e3937e446 Moreau, P. (Philippe)|||/items/3d8d9f42-9629-4e12-9854-43031d9b6332 Zweegman, S. (Sonja)|||/items/e3037369-fb2d-4527-bd35-f49dbd8ab08b Engelhardt, M. (Monika)|||/items/19022ea7-5d61-41b2-8552-38296d8afb2c Rosiñol, L. (Laura)|||/items/60f5826d-b5d8-4972-b968-ccda26113fbf |
| author |
Caers, J. (Jo)|||/items/403726c8-4135-42b4-995f-a3173e1e6e4a |
| author_facet |
Caers, J. (Jo)|||/items/403726c8-4135-42b4-995f-a3173e1e6e4a Paiva, B. (Bruno)|||/items/b2c3efc5-27e1-4425-b452-efba1522c1d5 Zamagni, E. (Elena)|||/items/3ed4ddd1-d487-41a8-ab7e-f23ebfbd71e4 Leleu, X. (Xavier)|||/items/aae83612-eb31-463f-b7e2-59e5d13fc75a Bladé, J. (Joan)|||/items/2e3393a4-11c5-4a58-8b64-52150839a266 Kristinsson, S.Y. (S. Y.)|||/items/c7617c3b-deff-40c6-a0be-5a9228b0a1b7 Touzeau, C. (C.)|||/items/859cd94f-84a8-48fe-9da0-00046e5341f1 Abildgaard, N. (N.)|||/items/35ad69ff-df3f-475d-95bd-4375f995dbdf Terpos, E. (Evangelos)|||/items/f7dbaa50-9ab3-42ba-bf5a-d80977a9f8d4 Heusschen, R. (R.)|||/items/4ea8a18c-7f2f-4a30-84a6-2bc146a95b9c Ocio, E.M. (Enrique M.)|||/items/2e2c579b-5c69-4327-bbef-0107e8ab4f2e Delforge, M. (Michel)|||/items/f642fb6d-d632-430b-9601-260fd0bf5b45 Sezer, O. (O.)|||/items/ca2ab2ab-f3b3-499f-8b6b-c77552a7ef04 Beksac, M. (Meral)|||/items/705a45fb-336b-4552-ab63-514429511250 Ludwig, H. (Heinz)|||/items/4626d464-635c-4aac-bffe-d9eeef1e4380 Merlini, G. (G.)|||/items/812d1f01-e28b-456a-952a-0a4e3937e446 Moreau, P. (Philippe)|||/items/3d8d9f42-9629-4e12-9854-43031d9b6332 Zweegman, S. (Sonja)|||/items/e3037369-fb2d-4527-bd35-f49dbd8ab08b Engelhardt, M. (Monika)|||/items/19022ea7-5d61-41b2-8552-38296d8afb2c Rosiñol, L. (Laura)|||/items/60f5826d-b5d8-4972-b968-ccda26113fbf |
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author |
| author2 |
Paiva, B. (Bruno)|||/items/b2c3efc5-27e1-4425-b452-efba1522c1d5 Zamagni, E. (Elena)|||/items/3ed4ddd1-d487-41a8-ab7e-f23ebfbd71e4 Leleu, X. (Xavier)|||/items/aae83612-eb31-463f-b7e2-59e5d13fc75a Bladé, J. (Joan)|||/items/2e3393a4-11c5-4a58-8b64-52150839a266 Kristinsson, S.Y. (S. Y.)|||/items/c7617c3b-deff-40c6-a0be-5a9228b0a1b7 Touzeau, C. (C.)|||/items/859cd94f-84a8-48fe-9da0-00046e5341f1 Abildgaard, N. (N.)|||/items/35ad69ff-df3f-475d-95bd-4375f995dbdf Terpos, E. (Evangelos)|||/items/f7dbaa50-9ab3-42ba-bf5a-d80977a9f8d4 Heusschen, R. (R.)|||/items/4ea8a18c-7f2f-4a30-84a6-2bc146a95b9c Ocio, E.M. (Enrique M.)|||/items/2e2c579b-5c69-4327-bbef-0107e8ab4f2e Delforge, M. (Michel)|||/items/f642fb6d-d632-430b-9601-260fd0bf5b45 Sezer, O. (O.)|||/items/ca2ab2ab-f3b3-499f-8b6b-c77552a7ef04 Beksac, M. (Meral)|||/items/705a45fb-336b-4552-ab63-514429511250 Ludwig, H. (Heinz)|||/items/4626d464-635c-4aac-bffe-d9eeef1e4380 Merlini, G. (G.)|||/items/812d1f01-e28b-456a-952a-0a4e3937e446 Moreau, P. (Philippe)|||/items/3d8d9f42-9629-4e12-9854-43031d9b6332 Zweegman, S. (Sonja)|||/items/e3037369-fb2d-4527-bd35-f49dbd8ab08b Engelhardt, M. (Monika)|||/items/19022ea7-5d61-41b2-8552-38296d8afb2c Rosiñol, L. (Laura)|||/items/60f5826d-b5d8-4972-b968-ccda26113fbf |
| author2_role |
author author author author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Dadun. Depósito Académico Digital Universidad de Navarra |
| dc.subject.none.fl_str_mv |
Solitary plasmacytoma Extramedullary plasmacytoma Myeloma Plasma cell dyscrasia PET/CT MRI Radiotherapy |
| topic |
Solitary plasmacytoma Extramedullary plasmacytoma Myeloma Plasma cell dyscrasia PET/CT MRI Radiotherapy |
| description |
Solitary plasmacytoma is an infrequent form of plasma cell dyscrasia that presents as a single mass of monoclonal plasma cells, located either extramedullary or intraosseous. In some patients, a bone marrow aspiration can detect a low monoclonal plasma cell infiltration which indicates a high risk of early progression to an overt myeloma disease. Before treatment initiation, whole body positron emission tomography–computed tomography or magnetic resonance imaging should be performed to exclude the presence of additional malignant lesions. For decades, treatment has been based on high-dose radiation, but studies exploring the potential benefit of systemic therapies for high-risk patients are urgently needed. In this review, a panel of expert European hematologists updates the recommendations on the diagnosis and management of patients with solitary plasmacytoma. |
| publishDate |
2018 |
| dc.date.none.fl_str_mv |
2018 2018-01-01 2018 2018-01-01 2023 2023-03-09 |
| dc.type.none.fl_str_mv |
journal article http://purl.org/coar/resource_type/c_6501 |
| dc.type.openaire.fl_str_mv |
info:eu-repo/semantics/article |
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article |
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https://hdl.handle.net/10171/65654 |
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https://hdl.handle.net/10171/65654 |
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Inglés eng |
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Inglés |
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eng |
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open access http://purl.org/coar/access_right/c_abf2 |
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info:eu-repo/semantics/openAccess |
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open access http://purl.org/coar/access_right/c_abf2 |
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openAccess |
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application/pdf |
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BioMed Central |
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BioMed Central |
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reponame:Dadun. Depósito Académico Digital de la Universidad de Navarra instname:Universidad de Navarra |
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Universidad de Navarra |
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Dadun. Depósito Académico Digital de la Universidad de Navarra |
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Dadun. Depósito Académico Digital de la Universidad de Navarra |
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15,301603 |