Primary plasmacytoma of the thyroid gland: a case report of a rare neoplasia
Extramedullary plasmacytoma comprises 3%-5% of all plasma cell neoplasms, and approximately 80% of the cases occur in the upper respiratory tract. Primary thyroid plasmacytomas (PTP) are rare tumors. The authors report a case of PTP in a male patient with dyspnea and dysphagia. Physical examination...
| Autores: | , , , |
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| Tipo de recurso: | informe técnico |
| Estado: | Versión publicada |
| Fecha de publicación: | 2012 |
| País: | Brasil |
| Institución: | Sociedade Brasileira de Patologia (SBP) |
| Repositorio: | Jornal Brasileiro de Patologia e Medicina Laboratorial (Online) |
| Idioma: | inglés |
| OAI Identifier: | oai:scielo:S1676-24442012000400009 |
| Acceso en línea: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442012000400009 |
| Access Level: | acceso abierto |
| Palabra clave: | Plasmacytoma Thyroid gland Multiple myeloma Immunohistochemistry |
| Sumario: | Extramedullary plasmacytoma comprises 3%-5% of all plasma cell neoplasms, and approximately 80% of the cases occur in the upper respiratory tract. Primary thyroid plasmacytomas (PTP) are rare tumors. The authors report a case of PTP in a male patient with dyspnea and dysphagia. Physical examination and computerized tomography (CT) scan revealed a solid tumor affecting the thyroid gland, measuring 12 cm in its greatest dimension. Surgical biopsy was performed. Microscopy revealed a hypercellular malignant neoplasm composed of round plasmacytoid cells arranged in solid nests, which showed a positive immunoexpression for CD138, epithelial membrane antigen (AME), kappa light chains and multiple myeloma oncogene 1 (MUM1). The diagnosis of PTP was accordingly established. |
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