CRISPR-RfxCas13d screening uncovers Bckdk as a post-translational regulator of maternal-to-zygotic transition in teleosts

[Data availability] RNA-seq, ATAC-seq, CUT&RUN, and SLAM-seq data have been deposited in GEO under accession code GSE268294 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE268294). Proteomics, phospho-proteomics, and isoleucine-leucine data have been deposited at MassIVE MSV000094733 Vali...

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Detalles Bibliográficos
Autores: Hernández-Huertas, Luis, Moreno-Sánchez, Ismael, Crespo-Cuadrado, Jesús, Vargas-Baco, Ana, Pescador, Gabriel da Silva, Zhang, Ying, Wen, Zhihui, Florens, Laurence, Santos-Pereira, José M., Bazzini, Ariel A., Moreno-Mateos, Miguel A.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/418163
Acceso en línea:http://hdl.handle.net/10261/418163
https://api.elsevier.com/content/abstract/scopus_id/105022469383
Access Level:acceso abierto
Palabra clave:Bckdk
CRISPR-RfxCas13d
Kinases
MZT
Zebrafish
Descripción
Sumario:[Data availability] RNA-seq, ATAC-seq, CUT&RUN, and SLAM-seq data have been deposited in GEO under accession code GSE268294 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE268294). Proteomics, phospho-proteomics, and isoleucine-leucine data have been deposited at MassIVE MSV000094733 Valine quantification data have been deposited at MassIVE MSV000094867. The source data of this paper are collected in the following database record: biostudies:S-SCDT-10_1038-S44318-025-00617-8.

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