Open problems in synthetic multicellularity

Multicellularity is one of the major evolutionary transitions, and its rise provided the ingredients for the emergence of a biosphere inhabited by complex organisms. Over the last decades, the potential for bioengineering multicellular systems has been instrumental in interrogating nature and explor...

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Detalles Bibliográficos
Autores: Solé Vicente, Ricard, 1962-, Conde Pueyo, Núria, 1983-, Pla, Jordi, García Ojalvo, Jordi, Montserrat Pulido, Núria, Levin, Michael
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10230/69672
Acceso en línea:http://hdl.handle.net/10230/69672
http://dx.doi.org/10.1038/s41540-024-00477-8
Access Level:acceso abierto
Palabra clave:Multicellular systems
Synthetic biology
Descripción
Sumario:Multicellularity is one of the major evolutionary transitions, and its rise provided the ingredients for the emergence of a biosphere inhabited by complex organisms. Over the last decades, the potential for bioengineering multicellular systems has been instrumental in interrogating nature and exploring novel paths to regeneration, disease, cognition, and behaviour. Here, we provide a list of open problems that encapsulate many of the ongoing and future challenges in the field and suggest conceptual approaches that may facilitate progress.