CD34 + Cell Selection versus Reduced-Intensity Conditioning and Unmodified Grafts for Allogeneic Hematopoietic Cell Transplantation in Patients Age

Reduced-intensity conditioning (RIC) and T cell depletion (TCD) through CD34 cell selection without the use of post-transplantation immunosuppression are 2 strategies used to reduce nonrelapse mortality (NRM) in older patients after allogeneic hematopoietic cell transplantation (allo-HCT). To compar...

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Detalles Bibliográficos
Autores: Barba, Pere|||0000-0001-7076-7969, Martino Bofarull, Rodrigo|||0000-0001-5143-4042, Zhou, Quin C., Cho, Christina, Castro-Malaspina, Hugo, Devlin, Sean M., Esquirol, Albert|||0000-0002-6062-5980, Giralt, Sergio, Jakubowski, Ann A., Caballero, Dolores|||0000-0002-9544-9614, Maloy, Molly, Papadopoulos, Esperanza B., Piñana, José Luis|||0000-0001-8533-2562, Fox, Maria Laura|||0000-0002-0062-6607, Márquez-Malaver, Francisco J., Valcárcel, David|||0000-0002-8747-078X, Solano, Carlos|||0000-0003-3702-0817, López-Corral, Lucía, Malouf Sierra, Jorge|||0000-0001-5185-520X, Perales, Miguel-Angel|||0000-0002-5910-4571
Tipo de recurso: artículo
Fecha de publicación:2018
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:286898
Acceso en línea:https://ddd.uab.cat/record/286898
https://dx.doi.org/urn:doi:10.1016/j.bbmt.2017.12.804
Access Level:acceso abierto
Palabra clave:Allogeneic hematopoietic cell transplantation
GVHD
RIC
T cell depletion
Descripción
Sumario:Reduced-intensity conditioning (RIC) and T cell depletion (TCD) through CD34 cell selection without the use of post-transplantation immunosuppression are 2 strategies used to reduce nonrelapse mortality (NRM) in older patients after allogeneic hematopoietic cell transplantation (allo-HCT). To compare the efficacy of the RIC and TCD approaches, we evaluated the outcomes of patients age.

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