Multiple myeloma and SARS-CoV-2 infection

There is limited information on the characteristics, prognostic factors, and outcomes of patients with multiple myeloma (MM) hospitalized with COVID-19. This retrospective case series investigated 167 patients reported from 73 hospitals within the Spanish Myeloma Collaborative Group network in March...

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Detalhes bibliográficos
Autores: Martínez-López, Joaquín|||0000-0001-7908-0063, Mateos, M. V.|||0000-0003-2390-1218, Encinas, C.|||0000-0002-9001-9754, Sureda, Anna|||0000-0002-1238-6970, Hernández Rivas, José Ángel|||0000-0003-4550-757X, Lopez de la Guía, A., Conde, Diego, Krsnik, Isabel|||0000-0002-2912-5072, Prieto, Elena|||0000-0002-3609-1210, Riaza Grau, R., Gironella, Mercedes|||0000-0002-8106-8909, Blanchard, María Jesús, Caminos, N., Fernández de Larrea, Carlos|||0000-0003-4930-9255, Senin, Alicia|||0000-0001-5075-8731, Escalante, F., de la Puerta, J. E.|||0000-0003-2563-7510, Giménez, E., Martínez-Barranco, P., Mateos, J. J., Casado Montero, Luis Felipe|||0000-0002-8171-0674, Bladé Creixenti, Juan|||0000-0002-4563-3405, Lahuerta, J. J.|||0000-0002-3393-9570, De la Cruz, Javier|||0000-0002-2010-4128, San Miguel, Jesús|||0000-0002-9183-4857
Formato: artículo
Fecha de publicación:2020
País:España
Recursos:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:236599
Acesso em linha:https://ddd.uab.cat/record/236599
https://dx.doi.org/urn:doi:10.1038/s41408-020-00372-5
Access Level:acceso abierto
Palavra-chave:Aged
Betacoronavirus
Comorbidity
Coronavirus Infections
Female
Hospitalization
Humans
Inpatients
Kidney
Male
Middle Aged
Multiple Myeloma
Pandemics
Pneumonia, Viral
Prognosis
Severity of Illness Index
Descrição
Resumo:There is limited information on the characteristics, prognostic factors, and outcomes of patients with multiple myeloma (MM) hospitalized with COVID-19. This retrospective case series investigated 167 patients reported from 73 hospitals within the Spanish Myeloma Collaborative Group network in March and April, 2020. Outcomes were compared with 167 randomly selected, contemporary, age-/sex-matched noncancer patients with COVID-19 admitted at six participating hospitals. Among MM and noncancer patients, median age was 71 years, and 57% of patients were male; 75 and 77% of patients, respectively, had at least one comorbidity. COVID-19 clinical severity was moderate-severe in 77 and 89% of patients and critical in 8 and 4%, respectively. Supplemental oxygen was required by 47 and 55% of MM and noncancer patients, respectively, and 21%/9% vs 8%/6% required noninvasive/invasive ventilation. Inpatient mortality was 34 and 23% in MM and noncancer patients, respectively. Among MM patients, inpatient mortality was 41% in males, 42% in patients aged.

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