Update on systemic treatment in early triple negative breast cancer

Triple negative breast cancer (TNBC) is a heterogeneous disease representing about 15% of all breast cancers. TNBC are usually high-grade histological tumors, and are generally more aggressive and difficult to treat due to the lack of targeted therapies available, and chemotherapy remains the standa...

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Detalles Bibliográficos
Autores: Núñez Abad, Martín, Calabuig Fariñas, Silvia, Lobo de Mena, Miriam, Godes Sanz de Bremond, María José, García González, Clara, Torres Martínez, Susana, García García, José Ángel, Iranzo González-Cruz, Vega, Camps Herrero, Carlos
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universidad Católica de Valencia San Vicente Mártir
Repositorio:RIUCV. Repositorio de la Universidad Católica de Valencia San Vicente Mártir
Idioma:inglés
OAI Identifier:oai:riucv.ucv.es:20.500.12466/3408
Acceso en línea:http://hdl.handle.net/20.500.12466/3408
Access Level:acceso abierto
Palabra clave:Chemotherapy
Immunotherapy
Neoadjuvant therapy
Precision medicine
Systemic treatment
Triple negative breast cancer
3201.01 Oncología
Descripción
Sumario:Triple negative breast cancer (TNBC) is a heterogeneous disease representing about 15% of all breast cancers. TNBC are usually high-grade histological tumors, and are generally more aggressive and difficult to treat due to the lack of targeted therapies available, and chemotherapy remains the standard treatment. There is a close relationship between pathological complete response after chemotherapy treatment and higher rates of disease-free survival and overall survival. In this review of systemic treatment in early triple negative breast cancer, our purpose is to analyze and compare different therapies, as well as to highlight the novelties of treatment in this breast cancer subtype.