Emerging roles of infiltrating granulocytes and monocytes in homeostasis.

The infiltration of naïve tissues by myeloid cells has been long related to their clearance and the physiological cell turnover, however, increasing evidence shows that they can additionally fulfill specific, non-immune functions in different tissues. There is also growing evidence to support that i...

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Detalles Bibliográficos
Autores: Groeneweg, Linda, Hidalgo, Andres, Alonso-Gonzalez, Noelia
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/11174
Acceso en línea:http://hdl.handle.net/20.500.12105/11174
Access Level:acceso abierto
Palabra clave:Cell Communication
Cytokines
Gene Expression
Granulocytes
Humans
Immunomodulation
Lung
Monocytes
Neutrophil Infiltration
Neutrophils
Descripción
Sumario:The infiltration of naïve tissues by myeloid cells has been long related to their clearance and the physiological cell turnover, however, increasing evidence shows that they can additionally fulfill specific, non-immune functions in different tissues. There is also growing evidence to support that infiltrated granulocytes and monocytes respond to different environments by modulating gene expression and cytokine production, which in turn contribute to the normal function of the host tissue. This review will address the roles of immigrated myeloid cells in different tissues and their crosstalk with the host tissue environments.