Uterine microbiome-low biomass and high expectations.

The existence of different bacterial communities throughout the female reproductive tract has challenged the traditional view of human fetal development as a sterile event. There is still no consensus on what physiological microbiota exists in the upper reproductive tract of the vast majority of wom...

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Detalhes bibliográficos
Autores: Garcia-Grau I, Simon C, Moreno I
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2019
País:España
Recursos:INCLIVA
Repositorio:r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
OAI Identifier:oai:incliva.fundanetsuite.com:p2601
Acesso em linha:https://incliva.portalinvestigacion.com/publicaciones/2601
Access Level:acceso abierto
Palavra-chave:uterus
endometrial microbiota
reproductive tract bacteria
female infertility
assisted reproductive technology
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spelling Uterine microbiome-low biomass and high expectations.Garcia-Grau ISimon CMoreno Iuterusendometrial microbiotareproductive tract bacteriafemale infertilityassisted reproductive technologyThe existence of different bacterial communities throughout the female reproductive tract has challenged the traditional view of human fetal development as a sterile event. There is still no consensus on what physiological microbiota exists in the upper reproductive tract of the vast majority of women who are not in periods of infection or pregnancy, and the role of bacteria that colonize the upper reproductive tract in uterine diseases or pregnancy outcomes is not well established. Despite published studies and advances in uterine microbiome sequencing, some study aspects-such as study design, sampling method, DNA extraction, sequencing methods, downstream analysis, and assignment of taxa-have not yet been improved and standardized. It is time to further investigate the uterine microbiome to increase our understanding of the female reproductive tract and to develop more personalized reproductive therapies, highlighting the potential importance of using microbiological assessment in infertile patients.OXFORD UNIV PRESS INC2019info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://incliva.portalinvestigacion.com/publicaciones/2601BIOLOGY OF REPRODUCTIONISSN: 00063363ISSNe: 15297268reponame:r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVAinstname:INCLIVAInglésinfo:eu-repo/semantics/openAccessoai:incliva.fundanetsuite.com:p26012026-06-07T16:35:31Z
dc.title.none.fl_str_mv Uterine microbiome-low biomass and high expectations.
title Uterine microbiome-low biomass and high expectations.
spellingShingle Uterine microbiome-low biomass and high expectations.
Garcia-Grau I
uterus
endometrial microbiota
reproductive tract bacteria
female infertility
assisted reproductive technology
title_short Uterine microbiome-low biomass and high expectations.
title_full Uterine microbiome-low biomass and high expectations.
title_fullStr Uterine microbiome-low biomass and high expectations.
title_full_unstemmed Uterine microbiome-low biomass and high expectations.
title_sort Uterine microbiome-low biomass and high expectations.
dc.creator.none.fl_str_mv Garcia-Grau I
Simon C
Moreno I
author Garcia-Grau I
author_facet Garcia-Grau I
Simon C
Moreno I
author_role author
author2 Simon C
Moreno I
author2_role author
author
dc.subject.none.fl_str_mv uterus
endometrial microbiota
reproductive tract bacteria
female infertility
assisted reproductive technology
topic uterus
endometrial microbiota
reproductive tract bacteria
female infertility
assisted reproductive technology
description The existence of different bacterial communities throughout the female reproductive tract has challenged the traditional view of human fetal development as a sterile event. There is still no consensus on what physiological microbiota exists in the upper reproductive tract of the vast majority of women who are not in periods of infection or pregnancy, and the role of bacteria that colonize the upper reproductive tract in uterine diseases or pregnancy outcomes is not well established. Despite published studies and advances in uterine microbiome sequencing, some study aspects-such as study design, sampling method, DNA extraction, sequencing methods, downstream analysis, and assignment of taxa-have not yet been improved and standardized. It is time to further investigate the uterine microbiome to increase our understanding of the female reproductive tract and to develop more personalized reproductive therapies, highlighting the potential importance of using microbiological assessment in infertile patients.
publishDate 2019
dc.date.none.fl_str_mv 2019
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://incliva.portalinvestigacion.com/publicaciones/2601
url https://incliva.portalinvestigacion.com/publicaciones/2601
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv OXFORD UNIV PRESS INC
publisher.none.fl_str_mv OXFORD UNIV PRESS INC
dc.source.none.fl_str_mv BIOLOGY OF REPRODUCTION
ISSN: 00063363
ISSNe: 15297268
reponame:r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname:INCLIVA
instname_str INCLIVA
reponame_str r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
collection r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.812429

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