La influencia del exposoma en el cáncer de piel

Skin cancer is the most frequent type of cancer in humans. While exposure to solar radiation is the most widely known and relevant causal factor, the different degrees of individual risk have not been fully elucidated. Epidemiological studies show how the risk of skin cancer is affected by other typ...

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Detalhes bibliográficos
Autores: Gracia-Cazaña, T., González, S., Parrado, C., Juarranz de la Fuente, Ángeles, Gilaberte, Y.
Formato: artículo
Fecha de publicación:2020
País:España
Recursos:Universidad Autónoma de Madrid
Repositorio:Biblos-e Archivo. Repositorio Institucional de la UAM
Idioma:español
OAI Identifier:oai:repositorio.uam.es:10486/714740
Acesso em linha:http://hdl.handle.net/10486/714740
https://dx.doi.org/10.1016/j.ad.2020.04.008
Access Level:acceso abierto
Palavra-chave:Exposome
melanoma
non melanoma skin cáncer
skin cancer
exposoma
cáncer de piel
Melanoma
Cáncer cutáneo no melanoma
Biología y Biomedicina / Biología
Descrição
Resumo:Skin cancer is the most frequent type of cancer in humans. While exposure to solar radiation is the most widely known and relevant causal factor, the different degrees of individual risk have not been fully elucidated. Epidemiological studies show how the risk of skin cancer is affected by other types of radiation (eg, ionizing radiation), pesticides, particulate matter in air pollution, toxins (eg, arsenic) in water and some foods. Some living entities, such as polyomavirus and human papillomavirus, can also cause specific types of cancer. Lastly, lifestyle factors such as stress, sleep, and exercise may play a role, although only a few studies shed light on these factors. The abovementioned factors make up the exposome of skin cancer, that is, the set of environmental exposures that, together with the genome and microbiome, determine the onset of disease