The self-similarity properties and multifractal analysis of DNA sequences

In this work is presented a pedagogical point of view of multifractal analysis deoxyribonucleic acid (DNA) sequences is presented. The DNA sequences are formed by 4 nucleotides (adenine, cytosine, guanine, and tymine). Following Jeffrey’s paper we associated a simple contractive function to each nuc...

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Bibliographic Details
Authors: Río Correa, J. L. del, López García, Javier, Durán Meza, G.
Format: article
Status:Published version
Publication Date:2019
Country:España
Institution:Universidad Pública de Navarra
Repository:Academica-e. Repositorio Institucional de la Universidad Pública de Navarra
OAI Identifier:oai:academica-e.unavarra.es:2454/40761
Online Access:https://hdl.handle.net/2454/40761
Access Level:Open access
Keyword:Multifractals
DNA sequences self-affine
Hutchinson operator
Holder exponents
Description
Summary:In this work is presented a pedagogical point of view of multifractal analysis deoxyribonucleic acid (DNA) sequences is presented. The DNA sequences are formed by 4 nucleotides (adenine, cytosine, guanine, and tymine). Following Jeffrey’s paper we associated a simple contractive function to each nucleotide, and constructed the Hutchinson’s operator W, which was used to build covers of different sizes of the unitary square Q, thus Wk (Q) is a cover of Q, conformed by 4k squares Qk of size 2−k, as each Qk corresponds to a unique subsequence of nucleotides with length k: b1b2...bk. Besides, it isobtained the optimal cover Ck to the fractal F generated for each DNA sequence was obtained. We made a multifractal decomposition of Ck in terms of the sets Jα conformed by the Qk’s with the same value of the Holder exponent α, and determined f(α), the Hausdorff dimension of Jα, using the curdling theorem.