Valorisation of the olive by-products phenolic compounds and their evaluation as therapeutic agents for ocular surface inflammatory diseases

This thesis aimed to valorize an environmentally hazardous agro-industrial by-product, the olive pomace, as source of phenolic compounds as potential therapeutic agents for dry eye disease. The effect of crude olive pomace extracts and their major pure phenolic compounds (oleuropein and hydroxytyros...

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Detalhes bibliográficos
Autor: Katsinas, Nicolaos
Formato: tesis doctoral
Estado:Versión publicada
Fecha de publicación:2022
País:España
Recursos:Universidad de Valladolid
Repositorio:UVaDOC. Repositorio Documental de la Universidad de Valladolid
OAI Identifier:oai:uvadoc.uva.es:10324/52860
Acesso em linha:https://doi.org/10.35376/10324/52860
https://uvadoc.uva.es/handle/10324/52860
Access Level:acceso abierto
Palavra-chave:Eye - Diseases
Ojos - Enfermedades
3201.09 Oftalmología
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spelling Valorisation of the olive by-products phenolic compounds and their evaluation as therapeutic agents for ocular surface inflammatory diseasesKatsinas, NicolaosEye - DiseasesOjos - Enfermedades3201.09 OftalmologíaThis thesis aimed to valorize an environmentally hazardous agro-industrial by-product, the olive pomace, as source of phenolic compounds as potential therapeutic agents for dry eye disease. The effect of crude olive pomace extracts and their major pure phenolic compounds (oleuropein and hydroxytyrosol), alone or in combination, was studied in the inflammatory and oxidative processes of the ocular surface and evaluating them as future topical ophthalmic products.Doctorado en Ciencias de la VisiónEnriquez De Salamanca Aladro, AmaliaRodríguez Rojo, SorayaUniversidad de Valladolid. Instituto Universitario de Oftalmobiología Aplicada (IOBA)2022info:eu-repo/semantics/doctoralThesisinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.35376/10324/52860https://uvadoc.uva.es/handle/10324/52860reponame:UVaDOC. Repositorio Documental de la Universidad de Valladolidinstname:Universidad de ValladolidEspañolinfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-nd/4.0/oai:uvadoc.uva.es:10324/528602026-06-13T12:44:47Z
dc.title.none.fl_str_mv Valorisation of the olive by-products phenolic compounds and their evaluation as therapeutic agents for ocular surface inflammatory diseases
title Valorisation of the olive by-products phenolic compounds and their evaluation as therapeutic agents for ocular surface inflammatory diseases
spellingShingle Valorisation of the olive by-products phenolic compounds and their evaluation as therapeutic agents for ocular surface inflammatory diseases
Katsinas, Nicolaos
Eye - Diseases
Ojos - Enfermedades
3201.09 Oftalmología
title_short Valorisation of the olive by-products phenolic compounds and their evaluation as therapeutic agents for ocular surface inflammatory diseases
title_full Valorisation of the olive by-products phenolic compounds and their evaluation as therapeutic agents for ocular surface inflammatory diseases
title_fullStr Valorisation of the olive by-products phenolic compounds and their evaluation as therapeutic agents for ocular surface inflammatory diseases
title_full_unstemmed Valorisation of the olive by-products phenolic compounds and their evaluation as therapeutic agents for ocular surface inflammatory diseases
title_sort Valorisation of the olive by-products phenolic compounds and their evaluation as therapeutic agents for ocular surface inflammatory diseases
dc.creator.none.fl_str_mv Katsinas, Nicolaos
author Katsinas, Nicolaos
author_facet Katsinas, Nicolaos
author_role author
dc.contributor.none.fl_str_mv Enriquez De Salamanca Aladro, Amalia
Rodríguez Rojo, Soraya
Universidad de Valladolid. Instituto Universitario de Oftalmobiología Aplicada (IOBA)
dc.subject.none.fl_str_mv Eye - Diseases
Ojos - Enfermedades
3201.09 Oftalmología
topic Eye - Diseases
Ojos - Enfermedades
3201.09 Oftalmología
description This thesis aimed to valorize an environmentally hazardous agro-industrial by-product, the olive pomace, as source of phenolic compounds as potential therapeutic agents for dry eye disease. The effect of crude olive pomace extracts and their major pure phenolic compounds (oleuropein and hydroxytyrosol), alone or in combination, was studied in the inflammatory and oxidative processes of the ocular surface and evaluating them as future topical ophthalmic products.
publishDate 2022
dc.date.none.fl_str_mv 2022
dc.type.none.fl_str_mv info:eu-repo/semantics/doctoralThesis
info:eu-repo/semantics/publishedVersion
format doctoralThesis
status_str publishedVersion
dc.identifier.none.fl_str_mv https://doi.org/10.35376/10324/52860
https://uvadoc.uva.es/handle/10324/52860
url https://doi.org/10.35376/10324/52860
https://uvadoc.uva.es/handle/10324/52860
dc.language.none.fl_str_mv Español
language_invalid_str_mv Español
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:UVaDOC. Repositorio Documental de la Universidad de Valladolid
instname:Universidad de Valladolid
instname_str Universidad de Valladolid
reponame_str UVaDOC. Repositorio Documental de la Universidad de Valladolid
collection UVaDOC. Repositorio Documental de la Universidad de Valladolid
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,300724

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