Valorisation of the olive by-products phenolic compounds and their evaluation as therapeutic agents for ocular surface inflammatory diseases
This thesis aimed to valorize an environmentally hazardous agro-industrial by-product, the olive pomace, as source of phenolic compounds as potential therapeutic agents for dry eye disease. The effect of crude olive pomace extracts and their major pure phenolic compounds (oleuropein and hydroxytyros...
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| Formato: | tesis doctoral |
| Estado: | Versión publicada |
| Fecha de publicación: | 2022 |
| País: | España |
| Recursos: | Universidad de Valladolid |
| Repositorio: | UVaDOC. Repositorio Documental de la Universidad de Valladolid |
| OAI Identifier: | oai:uvadoc.uva.es:10324/52860 |
| Acesso em linha: | https://doi.org/10.35376/10324/52860 https://uvadoc.uva.es/handle/10324/52860 |
| Access Level: | acceso abierto |
| Palavra-chave: | Eye - Diseases Ojos - Enfermedades 3201.09 Oftalmología |
| Resumo: | This thesis aimed to valorize an environmentally hazardous agro-industrial by-product, the olive pomace, as source of phenolic compounds as potential therapeutic agents for dry eye disease. The effect of crude olive pomace extracts and their major pure phenolic compounds (oleuropein and hydroxytyrosol), alone or in combination, was studied in the inflammatory and oxidative processes of the ocular surface and evaluating them as future topical ophthalmic products. |
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