Bimodal Nd-doped LuVO4 nanoprobes functionalized with polyacrilic acid for X-ray computed tomography and NIR luminescent imaging

This article belongs to the Section Synthesis, Interfaces and Nanostructures.

Detalhes bibliográficos
Autores: Núñez, Nuria O., Cussó, Fernando, Cantelar, Eugenio, Martín-Gracia, Beatriz, Fuente, Jesús M. de la, Corral, Ariadna, Balcerzyk, Marcin, Ocaña, Manuel
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2020
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositório:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/199476
Acesso em linha:http://hdl.handle.net/10261/199476
Access Level:Acceso aberto
Palavra-chave:Nanoparticles
LuVO4
Neodymium
Polyacrilic acid
NIR luminescence
X-ray computed tomography
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spelling Bimodal Nd-doped LuVO4 nanoprobes functionalized with polyacrilic acid for X-ray computed tomography and NIR luminescent imagingNúñez, Nuria O.Cussó, FernandoCantelar, EugenioMartín-Gracia, BeatrizFuente, Jesús M. de laCorral, AriadnaBalcerzyk, MarcinOcaña, ManuelNanoparticlesLuVO4NeodymiumPolyacrilic acidNIR luminescenceX-ray computed tomographyThis article belongs to the Section Synthesis, Interfaces and Nanostructures.Uniform Nd3+-doped LuVO4 nanophosphors have been synthesized for the first time in literature by using a poliol-basedmethod at 120 C fromNd3+ and vanadate precursors. After optimizing the Nd doping level, these phosphors present intense luminescence in the near-infrared biological windows. The X-ray attenuation capacity of the optimum nanophosphor has been found to be higher than that of a commercial X-ray computed tomography contrast agent. After surface coating with polyacrylic acid, such nanoparticles present high colloidal stability in physiological pHmediumand high cell viability. Because of these properties, the developedNd3+-doped LuVO4 nanoparticles have potential applications as a bimodal probe for NIR luminescent bioimaging and X-ray computed tomography.This work has been supported by the Spanish Ministry of Science, Innovation and Universities (MCIU/AEI/FEDER) under grant RTI2018-094426-B-I00, and Ministerio de Economía y Competitividad (MINECO) under project MAT2016-75716-C2-2-R.Peer reviewedMultidisciplinary Digital Publishing InstituteMinisterio de Ciencia, Innovación y Universidades (España)Ministerio de Economía y Competitividad (España)Cantelar, Eugenio [0000-0003-4293-8331]Fuente, Jesús M. de la [0000-0003-1081-8482]Balcerzyk, Marcine [0000-0001-6030-7416]Ocaña, Manuel [0000-0001-9989-606X]Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202020202020info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10261/199476reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/RTI2018-094426-B-I00info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/MAT2016-75716-C2-2-RRTI2018-094426-B-I00/AEI/10.13039/501100011033http://dx.doi.org/10.3390/nano10010149Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/1994762026-05-22T06:33:51Z
dc.title.none.fl_str_mv Bimodal Nd-doped LuVO4 nanoprobes functionalized with polyacrilic acid for X-ray computed tomography and NIR luminescent imaging
title Bimodal Nd-doped LuVO4 nanoprobes functionalized with polyacrilic acid for X-ray computed tomography and NIR luminescent imaging
spellingShingle Bimodal Nd-doped LuVO4 nanoprobes functionalized with polyacrilic acid for X-ray computed tomography and NIR luminescent imaging
Núñez, Nuria O.
Nanoparticles
LuVO4
Neodymium
Polyacrilic acid
NIR luminescence
X-ray computed tomography
title_short Bimodal Nd-doped LuVO4 nanoprobes functionalized with polyacrilic acid for X-ray computed tomography and NIR luminescent imaging
title_full Bimodal Nd-doped LuVO4 nanoprobes functionalized with polyacrilic acid for X-ray computed tomography and NIR luminescent imaging
title_fullStr Bimodal Nd-doped LuVO4 nanoprobes functionalized with polyacrilic acid for X-ray computed tomography and NIR luminescent imaging
title_full_unstemmed Bimodal Nd-doped LuVO4 nanoprobes functionalized with polyacrilic acid for X-ray computed tomography and NIR luminescent imaging
title_sort Bimodal Nd-doped LuVO4 nanoprobes functionalized with polyacrilic acid for X-ray computed tomography and NIR luminescent imaging
dc.creator.none.fl_str_mv Núñez, Nuria O.
Cussó, Fernando
Cantelar, Eugenio
Martín-Gracia, Beatriz
Fuente, Jesús M. de la
Corral, Ariadna
Balcerzyk, Marcin
Ocaña, Manuel
author Núñez, Nuria O.
author_facet Núñez, Nuria O.
Cussó, Fernando
Cantelar, Eugenio
Martín-Gracia, Beatriz
Fuente, Jesús M. de la
Corral, Ariadna
Balcerzyk, Marcin
Ocaña, Manuel
author_role author
author2 Cussó, Fernando
Cantelar, Eugenio
Martín-Gracia, Beatriz
Fuente, Jesús M. de la
Corral, Ariadna
Balcerzyk, Marcin
Ocaña, Manuel
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Ministerio de Ciencia, Innovación y Universidades (España)
Ministerio de Economía y Competitividad (España)
Cantelar, Eugenio [0000-0003-4293-8331]
Fuente, Jesús M. de la [0000-0003-1081-8482]
Balcerzyk, Marcine [0000-0001-6030-7416]
Ocaña, Manuel [0000-0001-9989-606X]
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Nanoparticles
LuVO4
Neodymium
Polyacrilic acid
NIR luminescence
X-ray computed tomography
topic Nanoparticles
LuVO4
Neodymium
Polyacrilic acid
NIR luminescence
X-ray computed tomography
description This article belongs to the Section Synthesis, Interfaces and Nanostructures.
publishDate 2020
dc.date.none.fl_str_mv 2020
2020
2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/199476
url http://hdl.handle.net/10261/199476
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
#PLACEHOLDER_PARENT_METADATA_VALUE#
#PLACEHOLDER_PARENT_METADATA_VALUE#
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/RTI2018-094426-B-I00
info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/MAT2016-75716-C2-2-R
RTI2018-094426-B-I00/AEI/10.13039/501100011033
http://dx.doi.org/10.3390/nano10010149

dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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