Molecular Imaging with Ga-68 Radio-Nanomaterials: Shedding Light on Nanoparticles

The combination of radioisotopes and nanomaterials is creating a new library of tracers for molecular imaging, exploiting the sensitivity of nuclear imaging techniques and the size-dependent properties of nanomaterials. This new approach is expanding the range of applications, including the possibil...

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Detalles Bibliográficos
Autores: Fernandez-Barahona, Irene, Munoz-Hernando, Maria, Pellico, Juan, Ruiz-Cabello, Jesus, Herranz, Fernando
Tipo de recurso: artículo
Fecha de publicación:2018
País:España
Institución:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/6542
Acceso en línea:http://hdl.handle.net/20.500.12105/6542
Access Level:acceso abierto
Palabra clave:Gallium-68
Radio-nanomaterials
Molecular imaging
Biomedical imaging
Nanoparticles
Radiochemistry
Nanomedicine
IRON-OXIDE NANOPARTICLES
POSITRON-EMISSION-TOMOGRAPHY
UP-CONVERSION NANOPARTICLES
SEMICONDUCTOR QUANTUM DOTS
SOMATOSTATIN RECEPTOR EXPRESSION
BRAIN-BARRIER PERMEABILITY
HUMAN-SERUM-ALBUMIN
IN-VIVO EVALUATION
DRUG-DELIVERY
MAGNETIC-RESONANCE
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network_acronym_str ES
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repository_id_str
spelling Molecular Imaging with Ga-68 Radio-Nanomaterials: Shedding Light on NanoparticlesFernandez-Barahona, IreneMunoz-Hernando, MariaPellico, JuanRuiz-Cabello, JesusHerranz, FernandoGallium-68Radio-nanomaterialsMolecular imagingBiomedical imagingNanoparticlesRadiochemistryNanomedicineIRON-OXIDE NANOPARTICLESPOSITRON-EMISSION-TOMOGRAPHYUP-CONVERSION NANOPARTICLESSEMICONDUCTOR QUANTUM DOTSSOMATOSTATIN RECEPTOR EXPRESSIONBRAIN-BARRIER PERMEABILITYHUMAN-SERUM-ALBUMININ-VIVO EVALUATIONDRUG-DELIVERYMAGNETIC-RESONANCEThe combination of radioisotopes and nanomaterials is creating a new library of tracers for molecular imaging, exploiting the sensitivity of nuclear imaging techniques and the size-dependent properties of nanomaterials. This new approach is expanding the range of applications, including the possibility of theranostics. Among the many different combinations, the use of Ga-68 as the radioisotope in the radio-nanomaterial is particularly convenient. The physicochemical properties of this isotope allow incorporating it into many materials with great chemical flexibility. Furthermore, its production from a benchtop generator eases the preparation of the tracer. Here, we review main results from the last years in which a nanomaterial has been radiolabeled with Ga-68. In thus process, we pay attention to the use of nanomaterials for biomedical imaging in general and main properties of this radioisotope. We study the main methods to carry out such radiolabeling and the most important applications for molecular imaging.Multidisciplinary Digital Publishing Institute (MDPI)Ministerio de Economía, Industria y Competitividad (España)Instituto de Salud Carlos III20182018-10-2620182018-01-0120182018-01-01journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/20.500.12105/6542reponame:Repisaludinstname:Instituto de Salud Carlos III (ISCIII)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Atribución 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:repisalud.isciii.es:20.500.12105/65422026-06-12T12:43:37Z
dc.title.none.fl_str_mv Molecular Imaging with Ga-68 Radio-Nanomaterials: Shedding Light on Nanoparticles
title Molecular Imaging with Ga-68 Radio-Nanomaterials: Shedding Light on Nanoparticles
spellingShingle Molecular Imaging with Ga-68 Radio-Nanomaterials: Shedding Light on Nanoparticles
Fernandez-Barahona, Irene
Gallium-68
Radio-nanomaterials
Molecular imaging
Biomedical imaging
Nanoparticles
Radiochemistry
Nanomedicine
IRON-OXIDE NANOPARTICLES
POSITRON-EMISSION-TOMOGRAPHY
UP-CONVERSION NANOPARTICLES
SEMICONDUCTOR QUANTUM DOTS
SOMATOSTATIN RECEPTOR EXPRESSION
BRAIN-BARRIER PERMEABILITY
HUMAN-SERUM-ALBUMIN
IN-VIVO EVALUATION
DRUG-DELIVERY
MAGNETIC-RESONANCE
title_short Molecular Imaging with Ga-68 Radio-Nanomaterials: Shedding Light on Nanoparticles
title_full Molecular Imaging with Ga-68 Radio-Nanomaterials: Shedding Light on Nanoparticles
title_fullStr Molecular Imaging with Ga-68 Radio-Nanomaterials: Shedding Light on Nanoparticles
title_full_unstemmed Molecular Imaging with Ga-68 Radio-Nanomaterials: Shedding Light on Nanoparticles
title_sort Molecular Imaging with Ga-68 Radio-Nanomaterials: Shedding Light on Nanoparticles
dc.creator.none.fl_str_mv Fernandez-Barahona, Irene
Munoz-Hernando, Maria
Pellico, Juan
Ruiz-Cabello, Jesus
Herranz, Fernando
author Fernandez-Barahona, Irene
author_facet Fernandez-Barahona, Irene
Munoz-Hernando, Maria
Pellico, Juan
Ruiz-Cabello, Jesus
Herranz, Fernando
author_role author
author2 Munoz-Hernando, Maria
Pellico, Juan
Ruiz-Cabello, Jesus
Herranz, Fernando
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Ministerio de Economía, Industria y Competitividad (España)
Instituto de Salud Carlos III
dc.subject.none.fl_str_mv Gallium-68
Radio-nanomaterials
Molecular imaging
Biomedical imaging
Nanoparticles
Radiochemistry
Nanomedicine
IRON-OXIDE NANOPARTICLES
POSITRON-EMISSION-TOMOGRAPHY
UP-CONVERSION NANOPARTICLES
SEMICONDUCTOR QUANTUM DOTS
SOMATOSTATIN RECEPTOR EXPRESSION
BRAIN-BARRIER PERMEABILITY
HUMAN-SERUM-ALBUMIN
IN-VIVO EVALUATION
DRUG-DELIVERY
MAGNETIC-RESONANCE
topic Gallium-68
Radio-nanomaterials
Molecular imaging
Biomedical imaging
Nanoparticles
Radiochemistry
Nanomedicine
IRON-OXIDE NANOPARTICLES
POSITRON-EMISSION-TOMOGRAPHY
UP-CONVERSION NANOPARTICLES
SEMICONDUCTOR QUANTUM DOTS
SOMATOSTATIN RECEPTOR EXPRESSION
BRAIN-BARRIER PERMEABILITY
HUMAN-SERUM-ALBUMIN
IN-VIVO EVALUATION
DRUG-DELIVERY
MAGNETIC-RESONANCE
description The combination of radioisotopes and nanomaterials is creating a new library of tracers for molecular imaging, exploiting the sensitivity of nuclear imaging techniques and the size-dependent properties of nanomaterials. This new approach is expanding the range of applications, including the possibility of theranostics. Among the many different combinations, the use of Ga-68 as the radioisotope in the radio-nanomaterial is particularly convenient. The physicochemical properties of this isotope allow incorporating it into many materials with great chemical flexibility. Furthermore, its production from a benchtop generator eases the preparation of the tracer. Here, we review main results from the last years in which a nanomaterial has been radiolabeled with Ga-68. In thus process, we pay attention to the use of nanomaterials for biomedical imaging in general and main properties of this radioisotope. We study the main methods to carry out such radiolabeling and the most important applications for molecular imaging.
publishDate 2018
dc.date.none.fl_str_mv 2018
2018-10-26
2018
2018-01-01
2018
2018-01-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12105/6542
url http://hdl.handle.net/20.500.12105/6542
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 4.0 Internacional
http://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 4.0 Internacional
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute (MDPI)
publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute (MDPI)
dc.source.none.fl_str_mv reponame:Repisalud
instname:Instituto de Salud Carlos III (ISCIII)
instname_str Instituto de Salud Carlos III (ISCIII)
reponame_str Repisalud
collection Repisalud
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869407688640692224
score 15,812429

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