GRADE equity guidelines 3

The aim of this paper is to describe a conceptual framework for how to consider health equity in the Grading Recommendations Assessment and Development Evidence (GRADE) guideline development process. Study Design and Setting Consensus-based guidance developed by the GRADE working group members and o...

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Detalhes bibliográficos
Autores: Welch, Vivian A., Akl, Elie A.|||0000-0002-3444-8618, Pottie, Kevin|||0000-0002-1874-8346, Ansari, Mohammed T., Briel, Matthias|||0000-0002-2070-5230, Christensen, Robin, Dans, Antonio, Dans, Leonila, Eslava-Schmalbach, J.|||0000-0003-1502-2918, Guyatt, Gordon|||0000-0003-2352-5718, Hultcrantz, Monica, Jull, Janet, Katikireddi, Srinivasa Vittal, Lang, Eddy, Matovinovic, Elizabeth, Meerpohl, Joerg J.|||0000-0002-1333-5403, Morton, Rachael|||0000-0001-7834-0572, Mosdol, Annhild, Murad, M.Hassan, Petkovic, Jennifer, Schünemann, Holger|||0000-0003-3211-8479, Sharaf, Ravi, Shea, Bev, Singh, Jasvinder A., Solà Arnau, Ivan|||0000-0003-0078-3706, Stanev, Roger, Stein, Airton|||0000-0002-8756-8699, Thabaneii, Lehana, Tonia, Thomy, Tristan, Mario|||0000-0001-6732-3398, Vitols, Sigurd, Watine, Joseph|||0000-0002-7881-0594, Tugwell, Peter|||0000-0001-5062-0556
Formato: artículo
Fecha de publicación:2017
País:España
Recursos:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:288428
Acesso em linha:https://ddd.uab.cat/record/288428
https://dx.doi.org/urn:doi:10.1016/j.jclinepi.2017.01.015
Access Level:acceso abierto
Palavra-chave:Applicability
Equity
GRADE
Guidelines
Health
Indirectness
Meta-analysis
Subgroup analysis
Systematic review
Descrição
Resumo:The aim of this paper is to describe a conceptual framework for how to consider health equity in the Grading Recommendations Assessment and Development Evidence (GRADE) guideline development process. Study Design and Setting Consensus-based guidance developed by the GRADE working group members and other methodologists. We developed consensus-based guidance to help address health equity when rating the certainty of synthesized evidence (i.e., quality of evidence). When health inequity is determined to be a concern by stakeholders, we propose five methods for explicitly assessing health equity: (1) include health equity as an outcome; (2) consider patient-important outcomes relevant to health equity; (3) assess differences in the relative effect size of the treatment; (4) assess differences in baseline risk and the differing impacts on absolute effects; and (5) assess indirectness of evidence to disadvantaged populations and/or settings. The most important priority for research on health inequity and guidelines is to identify and document examples where health equity has been considered explicitly in guidelines. Although there is a weak scientific evidence base for assessing health equity, this should not discourage the explicit consideration of how guidelines and recommendations affect the most vulnerable members of society.

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