Increased alpha-defensins 1-3 production by dendritic cells in HIV-infected individuals is associated with slower disease progression.

Defensins are natural endogenous antimicrobial peptides with potent anti-HIV activity and immuno-modulatory effects. We recently demonstrated that immature dendritic cells (DC) produce α-defensins1-3 and that α-defensins1-3 modulate DC generation and maturation. Since DC-HIV interaction plays a crit...

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Autores: Rodríguez García, Marta, Climent Vidal, Núria, Oliva, Harold, Casanova Güell, Víctor, Franco Fernández, Rafael, León García, Agathe, Gatell, José M., García, Felipe, Gallart, Teresa
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2010
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/42863
Acceso en línea:https://hdl.handle.net/2445/42863
Access Level:acceso abierto
Palabra clave:VIH (Virus)
Immunologia
HIV (Viruses)
Immunology
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spelling Increased alpha-defensins 1-3 production by dendritic cells in HIV-infected individuals is associated with slower disease progression.Rodríguez García, MartaCliment Vidal, NúriaOliva, HaroldCasanova Güell, VíctorFranco Fernández, RafaelLeón García, AgatheGatell, José M.García, FelipeGallart, TeresaVIH (Virus)ImmunologiaHIV (Viruses)ImmunologyDefensins are natural endogenous antimicrobial peptides with potent anti-HIV activity and immuno-modulatory effects. We recently demonstrated that immature dendritic cells (DC) produce α-defensins1-3 and that α-defensins1-3 modulate DC generation and maturation. Since DC-HIV interaction plays a critical role during the first steps of HIV infection, we investigated the possible impact of α-defensins1-3 production by DC on disease progression.Public Library of Science (PLoS)2010info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/42863Articles publicats en revistes (Bioquímica i Biomedicina Molecular)reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: http://dx.doi.org/10.1371/journal.pone.0009436PLoS One, 2010, vol. 5, num. 2, p. e9436-e9436http://dx.doi.org/10.1371/journal.pone.0009436cc-by (c) Rodríguez García, M. et al., 2010http://creativecommons.org/licenses/by/3.0/esinfo:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/428632026-05-27T06:46:51Z
dc.title.none.fl_str_mv Increased alpha-defensins 1-3 production by dendritic cells in HIV-infected individuals is associated with slower disease progression.
title Increased alpha-defensins 1-3 production by dendritic cells in HIV-infected individuals is associated with slower disease progression.
spellingShingle Increased alpha-defensins 1-3 production by dendritic cells in HIV-infected individuals is associated with slower disease progression.
Rodríguez García, Marta
VIH (Virus)
Immunologia
HIV (Viruses)
Immunology
title_short Increased alpha-defensins 1-3 production by dendritic cells in HIV-infected individuals is associated with slower disease progression.
title_full Increased alpha-defensins 1-3 production by dendritic cells in HIV-infected individuals is associated with slower disease progression.
title_fullStr Increased alpha-defensins 1-3 production by dendritic cells in HIV-infected individuals is associated with slower disease progression.
title_full_unstemmed Increased alpha-defensins 1-3 production by dendritic cells in HIV-infected individuals is associated with slower disease progression.
title_sort Increased alpha-defensins 1-3 production by dendritic cells in HIV-infected individuals is associated with slower disease progression.
dc.creator.none.fl_str_mv Rodríguez García, Marta
Climent Vidal, Núria
Oliva, Harold
Casanova Güell, Víctor
Franco Fernández, Rafael
León García, Agathe
Gatell, José M.
García, Felipe
Gallart, Teresa
author Rodríguez García, Marta
author_facet Rodríguez García, Marta
Climent Vidal, Núria
Oliva, Harold
Casanova Güell, Víctor
Franco Fernández, Rafael
León García, Agathe
Gatell, José M.
García, Felipe
Gallart, Teresa
author_role author
author2 Climent Vidal, Núria
Oliva, Harold
Casanova Güell, Víctor
Franco Fernández, Rafael
León García, Agathe
Gatell, José M.
García, Felipe
Gallart, Teresa
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv VIH (Virus)
Immunologia
HIV (Viruses)
Immunology
topic VIH (Virus)
Immunologia
HIV (Viruses)
Immunology
description Defensins are natural endogenous antimicrobial peptides with potent anti-HIV activity and immuno-modulatory effects. We recently demonstrated that immature dendritic cells (DC) produce α-defensins1-3 and that α-defensins1-3 modulate DC generation and maturation. Since DC-HIV interaction plays a critical role during the first steps of HIV infection, we investigated the possible impact of α-defensins1-3 production by DC on disease progression.
publishDate 2010
dc.date.none.fl_str_mv 2010
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/42863
url https://hdl.handle.net/2445/42863
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: http://dx.doi.org/10.1371/journal.pone.0009436
PLoS One, 2010, vol. 5, num. 2, p. e9436-e9436
http://dx.doi.org/10.1371/journal.pone.0009436
dc.rights.none.fl_str_mv cc-by (c) Rodríguez García, M. et al., 2010
http://creativecommons.org/licenses/by/3.0/es
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc-by (c) Rodríguez García, M. et al., 2010
http://creativecommons.org/licenses/by/3.0/es
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Public Library of Science (PLoS)
publisher.none.fl_str_mv Public Library of Science (PLoS)
dc.source.none.fl_str_mv Articles publicats en revistes (Bioquímica i Biomedicina Molecular)
reponame:Dipòsit Digital de la UB
instname:Universidad de Barcelona
instname_str Universidad de Barcelona
reponame_str Dipòsit Digital de la UB
collection Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.300719

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