Palladium and organocatalysis: An excellent recipe for asymmetric synthesis
The dual activation of simple substrates by the combination of organocatalysis and palladium catalysis has been successfully applied in a variety of different asymmetric transformations. Thus, the asymmetric α-allylation of carbonyl compounds, α-fluorination of acyl derivatives, decarboxylative prot...
| Autores: | , , , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 2013 |
| País: | España |
| Institución: | Universidad Autónoma de Madrid |
| Repositorio: | Biblos-e Archivo. Repositorio Institucional de la UAM |
| Idioma: | inglés |
| OAI Identifier: | oai:repositorio.uam.es:10486/667528 |
| Acceso en línea: | http://hdl.handle.net/10486/667528 https://dx.doi.org/10.3390/molecules180910108 |
| Access Level: | acceso abierto |
| Palabra clave: | Allylation Asymmetric synthesis Decarboxylative protonation Dual activation Fluorination Organocatalysis Palladium Tandem reaction Química |
| Sumario: | The dual activation of simple substrates by the combination of organocatalysis and palladium catalysis has been successfully applied in a variety of different asymmetric transformations. Thus, the asymmetric α-allylation of carbonyl compounds, α-fluorination of acyl derivatives, decarboxylative protonation of β-dicarbonyl compounds, cyclization reactions of alkynyl carbonyl compounds and β-functionalization of aldehydes have been efficiently achieved employing this double-catalytic methodology |
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