An extensive review on phenolic compounds and their potential estrogenic properties on skin physiology

Polyphenolic compounds constitute a diverse group of natural components commonly occurring in various plant species, known for their potential to exert both beneficial and detrimental effects. Additionally, these polyphenols have also been implicated as endocrine-disrupting (ED) chemicals, raising c...

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Autores: Rispo, Francesca, De Negri Atanasio, Giulia, Demori, Ilaria, Costa, Giosuè, Marchese, Emanuela, Perera-Del-Rosario, Simón, Serrano-Candelas, Eva, Palomino-Schätzlein, Martina, Perata, Elisabetta, Robino, Federica, Ferrari, Pier Francesco, Ferrando, Sara, Letasiova, Silvia, Markus, Jan, Zanotti-Russo, Matteo, Grasselli, Elena
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/354313
Acceso en línea:http://hdl.handle.net/10261/354313
https://api.elsevier.com/content/abstract/scopus_id/85186566498
Access Level:acceso abierto
Palabra clave:Skin physiology
Antioxidant
Cosmetics
Daidzein
Endocrine disruptors
Estrogen
Genistein
Polyphenols
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spelling An extensive review on phenolic compounds and their potential estrogenic properties on skin physiologyRispo, FrancescaDe Negri Atanasio, GiuliaDemori, IlariaCosta, GiosuèMarchese, EmanuelaPerera-Del-Rosario, SimónSerrano-Candelas, EvaPalomino-Schätzlein, MartinaPerata, ElisabettaRobino, FedericaFerrari, Pier FrancescoFerrando, SaraLetasiova, SilviaMarkus, JanZanotti-Russo, MatteoGrasselli, ElenaSkin physiologyAntioxidantCosmeticsDaidzeinEndocrine disruptorsEstrogenGenisteinPolyphenolsPolyphenolic compounds constitute a diverse group of natural components commonly occurring in various plant species, known for their potential to exert both beneficial and detrimental effects. Additionally, these polyphenols have also been implicated as endocrine-disrupting (ED) chemicals, raising concerns about their widespread use in the cosmetics industry. In this comprehensive review, we focus on the body of literature pertaining to the estrogenic properties of ED chemicals, with a particular emphasis on the interaction of isoflavones with estrogen receptors. Within this review, we aim to elucidate the multifaceted roles and effects of polyphenols on the skin, exploring their potential benefits as well as their capacity to act as ED agents. By delving into this intricate subject matter, we intend to provoke thoughtful consideration, effectively opening a Pandora's box of questions for the reader to ponder. Ultimately, we invite the reader to contemplate whether polyphenols should be regarded as friends or foes in the realm of skincare and endocrine disruption.This research was funded by: the Project National Center for the Development of New Technologies in Agriculture (Agritech), funded under the National Recovery and Resilience Plan (NRRP), Mission 4 Component 2 Investment 1.4-Call for tender No. 3,138 of 16 December 2021, rectified by Decree n. 3,175 of 18 December 2021 of the Italian Ministry of University and Research, funded by the European Union, NextGenerationEU, Project code_CN 00000022, Concession Decree No. 1032 of 17 June 2022, adopted by the Italian Ministry of University and Research, CUP B63D21015240004; the research was partially supported by Università degli Studi di Genova and Regione Liguria; (DGR 195/2021 ed al REG_AM_7979_2021). FR was supported by the PhD scholarship funded by Angel Consulting S.a.s Milano, Italy (ID Agreement: 1193-2021). PFF thanks the financial support provided by the Italian Ministry of University and Research for Programma Operativo Nazionale (PON) Ricerca e Innovazione 2014–2020—Azione IV.4—Dottorati e contratti di ricerca su tematiche dell’innovazione–FSE REACT-EU (D31B21008650007).Peer reviewedFrontiers MediaMinistero dell'Istruzione, dell'Università e della RicercaEuropean CommissionUniversità degli studi di GenovaAngel ConsultingConsejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202420242023info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10261/354313https://api.elsevier.com/content/abstract/scopus_id/85186566498reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Ingléshttps://doi.org/10.3389/fcell.2023.1305835Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/3543132026-05-22T06:33:51Z
dc.title.none.fl_str_mv An extensive review on phenolic compounds and their potential estrogenic properties on skin physiology
title An extensive review on phenolic compounds and their potential estrogenic properties on skin physiology
spellingShingle An extensive review on phenolic compounds and their potential estrogenic properties on skin physiology
Rispo, Francesca
Skin physiology
Antioxidant
Cosmetics
Daidzein
Endocrine disruptors
Estrogen
Genistein
Polyphenols
title_short An extensive review on phenolic compounds and their potential estrogenic properties on skin physiology
title_full An extensive review on phenolic compounds and their potential estrogenic properties on skin physiology
title_fullStr An extensive review on phenolic compounds and their potential estrogenic properties on skin physiology
title_full_unstemmed An extensive review on phenolic compounds and their potential estrogenic properties on skin physiology
title_sort An extensive review on phenolic compounds and their potential estrogenic properties on skin physiology
dc.creator.none.fl_str_mv Rispo, Francesca
De Negri Atanasio, Giulia
Demori, Ilaria
Costa, Giosuè
Marchese, Emanuela
Perera-Del-Rosario, Simón
Serrano-Candelas, Eva
Palomino-Schätzlein, Martina
Perata, Elisabetta
Robino, Federica
Ferrari, Pier Francesco
Ferrando, Sara
Letasiova, Silvia
Markus, Jan
Zanotti-Russo, Matteo
Grasselli, Elena
author Rispo, Francesca
author_facet Rispo, Francesca
De Negri Atanasio, Giulia
Demori, Ilaria
Costa, Giosuè
Marchese, Emanuela
Perera-Del-Rosario, Simón
Serrano-Candelas, Eva
Palomino-Schätzlein, Martina
Perata, Elisabetta
Robino, Federica
Ferrari, Pier Francesco
Ferrando, Sara
Letasiova, Silvia
Markus, Jan
Zanotti-Russo, Matteo
Grasselli, Elena
author_role author
author2 De Negri Atanasio, Giulia
Demori, Ilaria
Costa, Giosuè
Marchese, Emanuela
Perera-Del-Rosario, Simón
Serrano-Candelas, Eva
Palomino-Schätzlein, Martina
Perata, Elisabetta
Robino, Federica
Ferrari, Pier Francesco
Ferrando, Sara
Letasiova, Silvia
Markus, Jan
Zanotti-Russo, Matteo
Grasselli, Elena
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Ministero dell'Istruzione, dell'Università e della Ricerca
European Commission
Università degli studi di Genova
Angel Consulting
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Skin physiology
Antioxidant
Cosmetics
Daidzein
Endocrine disruptors
Estrogen
Genistein
Polyphenols
topic Skin physiology
Antioxidant
Cosmetics
Daidzein
Endocrine disruptors
Estrogen
Genistein
Polyphenols
description Polyphenolic compounds constitute a diverse group of natural components commonly occurring in various plant species, known for their potential to exert both beneficial and detrimental effects. Additionally, these polyphenols have also been implicated as endocrine-disrupting (ED) chemicals, raising concerns about their widespread use in the cosmetics industry. In this comprehensive review, we focus on the body of literature pertaining to the estrogenic properties of ED chemicals, with a particular emphasis on the interaction of isoflavones with estrogen receptors. Within this review, we aim to elucidate the multifaceted roles and effects of polyphenols on the skin, exploring their potential benefits as well as their capacity to act as ED agents. By delving into this intricate subject matter, we intend to provoke thoughtful consideration, effectively opening a Pandora's box of questions for the reader to ponder. Ultimately, we invite the reader to contemplate whether polyphenols should be regarded as friends or foes in the realm of skincare and endocrine disruption.
publishDate 2023
dc.date.none.fl_str_mv 2023
2024
2024
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/354313
https://api.elsevier.com/content/abstract/scopus_id/85186566498
url http://hdl.handle.net/10261/354313
https://api.elsevier.com/content/abstract/scopus_id/85186566498
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv https://doi.org/10.3389/fcell.2023.1305835

dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
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