European Guideline on Chronic Nausea and Vomiting-A UEG and ESNM Consensus for Clinical Management

Introduction: Chronic nausea and vomiting are symptoms of a wide range of gastrointestinal and non-gastrointestinal conditions. Diagnosis can be challenging and requires a systematic and well-structured approach. If the initial investigation for structural, toxic and metabolic disorders is negative,...

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Autores: Malagelada Prats, Carolina|||0000-0001-7097-1492, Keller, Jutta|||0000-0002-5884-1115, Sifrim, Daniel|||0000-0002-4894-0523, Serra Pueyo, Jordi|||0000-0003-2120-6270, Tack, Jan|||0000-0002-3206-6704, Mulak, Agata|||0000-0003-4678-8393, Stengel, Andreas, Aguilar, Ariadna|||0000-0002-2040-311X, Asbjorn, Drewes|||0000-0001-7465-964X, Josefsson, Axel, Bonaz, Bruno, Dumitrascu, Dan, Keszthelyi, Daniel|||0000-0001-9856-9980, Barba Orozco, Elizabeth|||0000-0002-5986-6592, Carbone, Florencia, Zerbib, Frank|||0000-0002-6802-2121, Marchegiani, Giovanni|||0000-0002-6824-4533, Hauser, Goran, Gourcerol, Guillaume, Tornblom, Hans|||0000-0003-2117-9874, Hammer, Heinz|||0000-0001-8683-4951, Aziz, Imran|||0000-0003-4313-0553, Matic, Jelena Rakic, Mendive Arbeloa, Juan Manuel|||0000-0001-8095-7707, Nikaki, Kornilia, Wauters, Lucas|||0000-0002-3195-4996, Alcalá González, Luis Gerardo|||0000-0003-3247-1539, Waluga, Marek, Jinga, Mariana, Corsetti, Maura, Rommel, Nathalie|||0000-0001-5675-7334, Shidrawi, Ray, De Giorgio, Roberto|||0000-0003-0867-5873, Kadirkamanathan, Sritharan, Surdea-Blaga, Teodora
Tipo de recurso: artículo
Fecha de publicación:2025
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:309922
Acceso en línea:https://ddd.uab.cat/record/309922
https://dx.doi.org/urn:doi:10.1002/ueg2.12711
Access Level:acceso abierto
Palabra clave:Delphi
Guidelines
Nausea
Vomiting
Descripción
Sumario:Introduction: Chronic nausea and vomiting are symptoms of a wide range of gastrointestinal and non-gastrointestinal conditions. Diagnosis can be challenging and requires a systematic and well-structured approach. If the initial investigation for structural, toxic and metabolic disorders is negative, digestive motility and gut-brain interaction disorders should be assessed. United European Gastroenterology (UEG) and the European Society for Neurogastroenterology and Motility (ESNM) identified the need for an updated, evidence-based clinical guideline for the management of chronic nausea and vomiting. Methods: A multidisciplinary team of experts in the field, including European specialists and national societies, participated in the development of the guideline. Relevant questions were addressed through a literature review and statements were developed and voted on according to a Delphi process. Results: Ninety-eight statements were identified and voted following the Delphi process. Overall agreement was high, although the grade of scientific evidence was low in many areas. Disagreement was more evident for some pharmacological treatment options. A diagnostic algorithm was developed, focussing on the differentiating features between gastrointestinal motility and gut-brain interaction disorders with predominant nausea and vomiting. Conclusion: These guidelines provide an evidence-based framework for the evaluation and treatment of patients with chronic nausea and vomiting.

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