Pathological mineralization of calcium phosphate
[eng] Based on the study of non-infected calcium phosphate renal calculi, solid concretions formed in simulated body fluid and calcific deposits formed in human aortic valves, two different mechanisms of hydroxyapatite (HAP) formation are described. In a mechanism, the formation of...
| Autores: | , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2015 |
| País: | España |
| Institución: | Universidad de las Islas Baleares |
| Repositorio: | Biblioteca Digital de les Illes Balears |
| OAI Identifier: | medicinaBalear:Medicina_Balear_2015v30n1_p043 |
| Acceso en línea: | http://ibdigital.uib.es/greenstone/sites/oai-site/collect/medicinaBalear/index/assoc/Medicina/_Balear_/2015v30n/1_p043.dir/Medicina_Balear_2015v30n1_p043.pdf http://ibdigital.uib.es/greenstone/library/collection/medicinaBalear/document/Medicina_Balear_2015v30n1_p043 |
| Access Level: | acceso abierto |
| Palabra clave: | Kidneys Calculi Medical sciences |
| Sumario: | [eng] Based on the study of non-infected calcium phosphate renal calculi, solid concretions formed in simulated body fluid and calcific deposits formed in human aortic valves, two different mechanisms of hydroxyapatite (HAP) formation are described. In a mechanism, the formation of spherical HAP particles takes place via aggregation of Posner’s clusters present in the liquid, after reaching a certain size gradually settled in the liquid and became incorporated into developing concretion. In the other mechanism, the microcolumnar HAP crystals were nucleated on randomly distributed detritus of organic origin embedded in the compact phase. Keywords: Biological hydroxyapatite, formation mechanism, renal calculi, aortic valve, body fluid |
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