Recommendations for Improving the Quality of Rare Disease Registries

Rare diseases (RD) patient registries are powerful instruments that help develop clinical research, facilitate the planning of appropriate clinical trials, improve patient care, and support healthcare management. They constitute a key information system that supports the activities of European Refer...

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Autores: Kodra, Yllka, Weinbach, Jérôme, Posada De la Paz, Manuel, Coi, Alessio, Lemonnier, S Lydie, van Enckevort, David, Roos, Marco, Jacobsen, Annika, Cornet, Ronald, Ahmed, S Faisal, Bros-Facer, Virginie, Popa, Veronica, Van Meel, Marieke, Renault, Daniel, von Gizycki, Rainald, Santoro, Michele, Landais, Paul, Torreri, Paola, Carta, Claudio, Mascalzoni, Deborah, Gainotti, Sabina, Lopez-Martin, Estrella, Ambrosini, Anna, Müller, Heimo, Reis, Robert, Bianchi, Fabrizio, Rubinstein, Yaffa, Lochmüller, Hanns, Taruscio, Domenica
Tipo de recurso: artículo
Fecha de publicación:2018
País:España
Institución:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/8902
Acceso en línea:http://hdl.handle.net/20.500.12105/8902
Access Level:acceso abierto
Palabra clave:Biomedical Research
Computational Biology
Data Accuracy
Europe
Humans
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spelling Recommendations for Improving the Quality of Rare Disease RegistriesKodra, YllkaWeinbach, JérômePosada De la Paz, ManuelCoi, AlessioLemonnier, S Lydievan Enckevort, DavidRoos, MarcoJacobsen, AnnikaCornet, RonaldAhmed, S FaisalBros-Facer, VirginiePopa, VeronicaVan Meel, MariekeRenault, Danielvon Gizycki, RainaldSantoro, MicheleLandais, PaulTorreri, PaolaCarta, ClaudioMascalzoni, DeborahGainotti, SabinaLopez-Martin, EstrellaAmbrosini, AnnaMüller, HeimoReis, RobertBianchi, FabrizioRubinstein, YaffaLochmüller, HannsTaruscio, DomenicaBiomedical ResearchComputational BiologyData AccuracyEuropeHumansRare diseases (RD) patient registries are powerful instruments that help develop clinical research, facilitate the planning of appropriate clinical trials, improve patient care, and support healthcare management. They constitute a key information system that supports the activities of European Reference Networks (ERNs) on rare diseases. A rapid proliferation of RD registries has occurred during the last years and there is a need to develop guidance for the minimum requirements, recommendations and standards necessary to maintain a high-quality registry. In response to these heterogeneities, in the framework of RD-Connect, a European platform connecting databases, registries, biobanks and clinical bioinformatics for rare disease research, we report on a list of recommendations, developed by a group of experts, including members of patient organizations, to be used as a framework for improving the quality of RD registries. This list includes aspects of governance, Findable, Accessible, Interoperable and Reusable (FAIR) data and information, infrastructure, documentation, training, and quality audit. The list is intended to be used by established as well as new RD registries. Further work includes the development of a toolkit to enable continuous assessment and improvement of their organizational and data quality.Multidisciplinary Digital Publishing Institute (MDPI)Unión Europea. Comisión Europea. 7 Programa MarcoConsumers, Health, Agriculture and Food Executive AgencyUnión Europea. European Cooperation in Science and Technology (COST)20202020-01-1520182018-01-0120182018-01-01research articlehttp://purl.org/coar/resource_type/c_2df8fbb1VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/20.500.12105/8902reponame:Repisaludinstname:Instituto de Salud Carlos III (ISCIII)InglésengEC 305444 Not availableEC 777215 Not availableopen accesshttp://purl.org/coar/access_right/c_abf2Atribución 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:repisalud.isciii.es:20.500.12105/89022026-06-12T12:43:37Z
dc.title.none.fl_str_mv Recommendations for Improving the Quality of Rare Disease Registries
title Recommendations for Improving the Quality of Rare Disease Registries
spellingShingle Recommendations for Improving the Quality of Rare Disease Registries
Kodra, Yllka
Biomedical Research
Computational Biology
Data Accuracy
Europe
Humans
title_short Recommendations for Improving the Quality of Rare Disease Registries
title_full Recommendations for Improving the Quality of Rare Disease Registries
title_fullStr Recommendations for Improving the Quality of Rare Disease Registries
title_full_unstemmed Recommendations for Improving the Quality of Rare Disease Registries
title_sort Recommendations for Improving the Quality of Rare Disease Registries
dc.creator.none.fl_str_mv Kodra, Yllka
Weinbach, Jérôme
Posada De la Paz, Manuel
Coi, Alessio
Lemonnier, S Lydie
van Enckevort, David
Roos, Marco
Jacobsen, Annika
Cornet, Ronald
Ahmed, S Faisal
Bros-Facer, Virginie
Popa, Veronica
Van Meel, Marieke
Renault, Daniel
von Gizycki, Rainald
Santoro, Michele
Landais, Paul
Torreri, Paola
Carta, Claudio
Mascalzoni, Deborah
Gainotti, Sabina
Lopez-Martin, Estrella
Ambrosini, Anna
Müller, Heimo
Reis, Robert
Bianchi, Fabrizio
Rubinstein, Yaffa
Lochmüller, Hanns
Taruscio, Domenica
author Kodra, Yllka
author_facet Kodra, Yllka
Weinbach, Jérôme
Posada De la Paz, Manuel
Coi, Alessio
Lemonnier, S Lydie
van Enckevort, David
Roos, Marco
Jacobsen, Annika
Cornet, Ronald
Ahmed, S Faisal
Bros-Facer, Virginie
Popa, Veronica
Van Meel, Marieke
Renault, Daniel
von Gizycki, Rainald
Santoro, Michele
Landais, Paul
Torreri, Paola
Carta, Claudio
Mascalzoni, Deborah
Gainotti, Sabina
Lopez-Martin, Estrella
Ambrosini, Anna
Müller, Heimo
Reis, Robert
Bianchi, Fabrizio
Rubinstein, Yaffa
Lochmüller, Hanns
Taruscio, Domenica
author_role author
author2 Weinbach, Jérôme
Posada De la Paz, Manuel
Coi, Alessio
Lemonnier, S Lydie
van Enckevort, David
Roos, Marco
Jacobsen, Annika
Cornet, Ronald
Ahmed, S Faisal
Bros-Facer, Virginie
Popa, Veronica
Van Meel, Marieke
Renault, Daniel
von Gizycki, Rainald
Santoro, Michele
Landais, Paul
Torreri, Paola
Carta, Claudio
Mascalzoni, Deborah
Gainotti, Sabina
Lopez-Martin, Estrella
Ambrosini, Anna
Müller, Heimo
Reis, Robert
Bianchi, Fabrizio
Rubinstein, Yaffa
Lochmüller, Hanns
Taruscio, Domenica
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Unión Europea. Comisión Europea. 7 Programa Marco
Consumers, Health, Agriculture and Food Executive Agency
Unión Europea. European Cooperation in Science and Technology (COST)

dc.subject.none.fl_str_mv Biomedical Research
Computational Biology
Data Accuracy
Europe
Humans
topic Biomedical Research
Computational Biology
Data Accuracy
Europe
Humans
description Rare diseases (RD) patient registries are powerful instruments that help develop clinical research, facilitate the planning of appropriate clinical trials, improve patient care, and support healthcare management. They constitute a key information system that supports the activities of European Reference Networks (ERNs) on rare diseases. A rapid proliferation of RD registries has occurred during the last years and there is a need to develop guidance for the minimum requirements, recommendations and standards necessary to maintain a high-quality registry. In response to these heterogeneities, in the framework of RD-Connect, a European platform connecting databases, registries, biobanks and clinical bioinformatics for rare disease research, we report on a list of recommendations, developed by a group of experts, including members of patient organizations, to be used as a framework for improving the quality of RD registries. This list includes aspects of governance, Findable, Accessible, Interoperable and Reusable (FAIR) data and information, infrastructure, documentation, training, and quality audit. The list is intended to be used by established as well as new RD registries. Further work includes the development of a toolkit to enable continuous assessment and improvement of their organizational and data quality.
publishDate 2018
dc.date.none.fl_str_mv 2018
2018-01-01
2018
2018-01-01
2020
2020-01-15
dc.type.none.fl_str_mv research article
http://purl.org/coar/resource_type/c_2df8fbb1
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12105/8902
url http://hdl.handle.net/20.500.12105/8902
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv EC 305444 Not available
EC 777215 Not available
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 4.0 Internacional
http://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 4.0 Internacional
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute (MDPI)
publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute (MDPI)
dc.source.none.fl_str_mv reponame:Repisalud
instname:Instituto de Salud Carlos III (ISCIII)
instname_str Instituto de Salud Carlos III (ISCIII)
reponame_str Repisalud
collection Repisalud
repository.name.fl_str_mv
repository.mail.fl_str_mv
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