SARS-CoV-2 Vaccination Coverage and Factors Associated with Low Uptake in a Cohort of People Living with HIV

People living with HIV (PLWH) are prioritised for SARS-CoV-2 vaccination due to their vulnerability to severe COVID-19. Therefore, the epidemiological surveillance of vaccination coverage and the timely identification of suboptimally vaccinated PLWH is vital. We assessed SARS-CoV-2 vaccination cover...

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Authors: Nomah, Daniel Kwakye, Llibre, Josep Maria, Díaz, Yesika, Moreno Martín, Sergio, Aceiton, Jordi, Bruguera, Andreu, Gutiérrez Macià, Maria, Imaz, Arkaitz, Suanzes, Paula, Navarro, Gemma, Orti, Amat, Miró Meda, José M. (José María), 1956-, Casabona, Jordi, Reyes Urueña, Juliana, The Piscis Study Group
Format: article
Status:Published version
Publication Date:2022
Country:España
Institution:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repository:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/188980
Online Access:https://hdl.handle.net/2445/188980
Access Level:Open access
Keyword:COVID-19
Vacunació
Vaccination
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spelling SARS-CoV-2 Vaccination Coverage and Factors Associated with Low Uptake in a Cohort of People Living with HIVNomah, Daniel KwakyeLlibre, Josep MariaDíaz, YesikaMoreno Martín, SergioAceiton, JordiBruguera, AndreuGutiérrez Macià, MariaImaz, ArkaitzSuanzes, PaulaNavarro, GemmaOrti, AmatMiró Meda, José M. (José María), 1956-Casabona, JordiReyes Urueña, JulianaThe Piscis Study GroupCOVID-19VacunacióCOVID-19VaccinationPeople living with HIV (PLWH) are prioritised for SARS-CoV-2 vaccination due to their vulnerability to severe COVID-19. Therefore, the epidemiological surveillance of vaccination coverage and the timely identification of suboptimally vaccinated PLWH is vital. We assessed SARS-CoV-2 vaccination coverage and factors associated with under-vaccination among PLWH in Catalonia, Spain. As of 11.12.2021, 9945/14942 PLWH (66.6%) had received >= 1 dose of a SARS-CoV-2 vaccine. Non-Spanish origin (adjusted odds ratio (aOR) 0.64, 95% CI 0.59-0.70), CD4 count of 200-349 cells/mu L (aOR 0.74, 95% CI 0.64-0.86) or 350-499 cells/mu L (aOR 0.79, 95% CI 0.70-0.88), detectable plasma HIV-RNA (aOR 0.61 95% CI 0.53-0.70), and previous SARS-CoV-2 diagnosis (aOR 0.58 95% CI 0.51-0.65) were associated with under-vaccination. SARS-CoV-2 diagnosis (437 [9.5%] vs. 323 [3.5%], p < 0.001), associated hospitalisations (10 [2.3%] vs. 0 [0%], p < 0.001), intensive care unit admissions (6 [1.4%] vs. 0 [0%], p < 0.001), and deaths (10 [2.3%] vs. 0 [0%], p < 0.001) were higher among unvaccinated PLWH. Vaccination coverage was lower among PLWH with a CD4 count >200 cells/mu L, detectable plasma HIV-RNA, previous SARS-CoV-2 diagnosis, and migrants. SARS-CoV-2 diagnosis, associated hospitalisations, and deaths among PLWH were lower among the vaccinated compared with the unvaccinated. SARS-CoV-2 vaccination prioritisation has not completely reached vulnerable PLWH with poorer prognosis. This information can be used to inform public health strategies.MDPI AG2022202220222022info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion12 p.application/pdfhttps://hdl.handle.net/2445/188980Articles publicats en revistes (Medicina)reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésReproducció del document publicat a: https://doi.org/10.3390/microorganisms10081666Microorganisms, 2022https://doi.org/10.3390/microorganisms10081666cc by (c) Nomah, Daniel Kwakye et al., 2022http://creativecommons.org/licenses/by/3.0/es/info:eu-repo/semantics/openAccessoai:recercat.cat:2445/1889802026-05-29T05:05:01Z
dc.title.none.fl_str_mv SARS-CoV-2 Vaccination Coverage and Factors Associated with Low Uptake in a Cohort of People Living with HIV
title SARS-CoV-2 Vaccination Coverage and Factors Associated with Low Uptake in a Cohort of People Living with HIV
spellingShingle SARS-CoV-2 Vaccination Coverage and Factors Associated with Low Uptake in a Cohort of People Living with HIV
Nomah, Daniel Kwakye
COVID-19
Vacunació
COVID-19
Vaccination
title_short SARS-CoV-2 Vaccination Coverage and Factors Associated with Low Uptake in a Cohort of People Living with HIV
title_full SARS-CoV-2 Vaccination Coverage and Factors Associated with Low Uptake in a Cohort of People Living with HIV
title_fullStr SARS-CoV-2 Vaccination Coverage and Factors Associated with Low Uptake in a Cohort of People Living with HIV
title_full_unstemmed SARS-CoV-2 Vaccination Coverage and Factors Associated with Low Uptake in a Cohort of People Living with HIV
title_sort SARS-CoV-2 Vaccination Coverage and Factors Associated with Low Uptake in a Cohort of People Living with HIV
dc.creator.none.fl_str_mv Nomah, Daniel Kwakye
Llibre, Josep Maria
Díaz, Yesika
Moreno Martín, Sergio
Aceiton, Jordi
Bruguera, Andreu
Gutiérrez Macià, Maria
Imaz, Arkaitz
Suanzes, Paula
Navarro, Gemma
Orti, Amat
Miró Meda, José M. (José María), 1956-
Casabona, Jordi
Reyes Urueña, Juliana
The Piscis Study Group
author Nomah, Daniel Kwakye
author_facet Nomah, Daniel Kwakye
Llibre, Josep Maria
Díaz, Yesika
Moreno Martín, Sergio
Aceiton, Jordi
Bruguera, Andreu
Gutiérrez Macià, Maria
Imaz, Arkaitz
Suanzes, Paula
Navarro, Gemma
Orti, Amat
Miró Meda, José M. (José María), 1956-
Casabona, Jordi
Reyes Urueña, Juliana
The Piscis Study Group
author_role author
author2 Llibre, Josep Maria
Díaz, Yesika
Moreno Martín, Sergio
Aceiton, Jordi
Bruguera, Andreu
Gutiérrez Macià, Maria
Imaz, Arkaitz
Suanzes, Paula
Navarro, Gemma
Orti, Amat
Miró Meda, José M. (José María), 1956-
Casabona, Jordi
Reyes Urueña, Juliana
The Piscis Study Group
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv COVID-19
Vacunació
COVID-19
Vaccination
topic COVID-19
Vacunació
COVID-19
Vaccination
description People living with HIV (PLWH) are prioritised for SARS-CoV-2 vaccination due to their vulnerability to severe COVID-19. Therefore, the epidemiological surveillance of vaccination coverage and the timely identification of suboptimally vaccinated PLWH is vital. We assessed SARS-CoV-2 vaccination coverage and factors associated with under-vaccination among PLWH in Catalonia, Spain. As of 11.12.2021, 9945/14942 PLWH (66.6%) had received >= 1 dose of a SARS-CoV-2 vaccine. Non-Spanish origin (adjusted odds ratio (aOR) 0.64, 95% CI 0.59-0.70), CD4 count of 200-349 cells/mu L (aOR 0.74, 95% CI 0.64-0.86) or 350-499 cells/mu L (aOR 0.79, 95% CI 0.70-0.88), detectable plasma HIV-RNA (aOR 0.61 95% CI 0.53-0.70), and previous SARS-CoV-2 diagnosis (aOR 0.58 95% CI 0.51-0.65) were associated with under-vaccination. SARS-CoV-2 diagnosis (437 [9.5%] vs. 323 [3.5%], p < 0.001), associated hospitalisations (10 [2.3%] vs. 0 [0%], p < 0.001), intensive care unit admissions (6 [1.4%] vs. 0 [0%], p < 0.001), and deaths (10 [2.3%] vs. 0 [0%], p < 0.001) were higher among unvaccinated PLWH. Vaccination coverage was lower among PLWH with a CD4 count >200 cells/mu L, detectable plasma HIV-RNA, previous SARS-CoV-2 diagnosis, and migrants. SARS-CoV-2 diagnosis, associated hospitalisations, and deaths among PLWH were lower among the vaccinated compared with the unvaccinated. SARS-CoV-2 vaccination prioritisation has not completely reached vulnerable PLWH with poorer prognosis. This information can be used to inform public health strategies.
publishDate 2022
dc.date.none.fl_str_mv 2022
2022
2022
2022
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/188980
url https://hdl.handle.net/2445/188980
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.3390/microorganisms10081666
Microorganisms, 2022
https://doi.org/10.3390/microorganisms10081666
dc.rights.none.fl_str_mv cc by (c) Nomah, Daniel Kwakye et al., 2022
http://creativecommons.org/licenses/by/3.0/es/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc by (c) Nomah, Daniel Kwakye et al., 2022
http://creativecommons.org/licenses/by/3.0/es/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 12 p.
application/pdf
dc.publisher.none.fl_str_mv MDPI AG
publisher.none.fl_str_mv MDPI AG
dc.source.none.fl_str_mv Articles publicats en revistes (Medicina)
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,30052

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