SARS-CoV-2 Vaccination Coverage and Factors Associated with Low Uptake in a Cohort of People Living with HIV

People living with HIV (PLWH) are prioritised for SARS-CoV-2 vaccination due to their vulnerability to severe COVID-19. Therefore, the epidemiological surveillance of vaccination coverage and the timely identification of suboptimally vaccinated PLWH is vital. We assessed SARS-CoV-2 vaccination cover...

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Detalhes bibliográficos
Autores: Nomah, Daniel Kwakye|||0000-0002-3988-9316, Llibre, Josep M.|||0000-0002-7158-6753, Díaz, Yesika|||0000-0002-3727-7340, Moreno-Fornés, Sergio|||0000-0001-9441-1799, Aceitón, Jordi|||0000-0001-8048-513X, Bruguera Riera, Andreu|||0000-0002-7524-0768, Gutiérrez-Macià, Maria, Imaz, Arkaitz|||0000-0001-8411-1952, Suanzes, Paula|||0000-0002-6871-0098, Navarro Rubio, Gemma|||0000-0002-7195-9046, Orti, Amat, Miró, José M|||0000-0001-8057-7755, Casabona-Barbarà, Jordi|||0000-0003-4816-5536, Reyes-Urueña, Juliana|||0000-0002-3122-6518
Formato: artículo
Fecha de publicación:2022
País:España
Recursos:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:282043
Acesso em linha:https://ddd.uab.cat/record/282043
https://dx.doi.org/urn:doi:10.3390/microorganisms10081666
Access Level:acceso abierto
Palavra-chave:Coronavirus disease 2019 (COVID-19)
HIV
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Vaccination
Vaccine effectiveness
Descrição
Resumo:People living with HIV (PLWH) are prioritised for SARS-CoV-2 vaccination due to their vulnerability to severe COVID-19. Therefore, the epidemiological surveillance of vaccination coverage and the timely identification of suboptimally vaccinated PLWH is vital. We assessed SARS-CoV-2 vaccination coverage and factors associated with under-vaccination among PLWH in Catalonia, Spain. As of 11.12.2021, 9945/14942 PLWH (66.6%) had received ≥1 dose of a SARS-CoV-2 vaccine. Non-Spanish origin (adjusted odds ratio (aOR) 0.64, 95% CI 0.59-0.70), CD4 count of 200-349 cells/μL (aOR 0.74, 95% CI 0.64-0.86) or 350-499 cells/μL (aOR 0.79, 95% CI 0.70-0.88), detectable plasma HIV-RNA (aOR 0.61 95% CI 0.53-0.70), and previous SARS-CoV-2 diagnosis (aOR 0.58 95% CI 0.51-0.65) were associated with under-vaccination. SARS-CoV-2 diagnosis (437 [9.5%] vs. 323 [3.5%], p < 0.001), associated hospitalisations (10 [2.3%] vs. 0 [0%], p < 0.001), intensive care unit admissions (6 [1.4%] vs. 0 [0%], p < 0.001), and deaths (10 [2.3%] vs. 0 [0%], p < 0.001) were higher among unvaccinated PLWH. Vaccination coverage was lower among PLWH with a CD4 count

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