Additional metabolic effects of bariatric surgery in patients with a poor mid-term weight loss response: a 5-year follow-up study

To ascertain the 5-year metabolic effects of bariatric surgery in poor weight loss (WL) responders and establish associated factors. Methods: Retrospective analysis of a non-randomised prospective cohort of bariatric surgery patients completing a 5-year follow-up. Mid-term poor WL was considered whe...

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Detalles Bibliográficos
Autores: Benaiges Foix, David, Bisbe Maria, Pedro-Botet, Juan, Vargas-Machuca, Aleix de, Ramón Moros, José Manuel, Pera Román, Manuel, Villatoro Moreno, Montserrat, Fontane Francia, Laia, Julià, Helena, Climent, Elisenda, Castañer, Olga, Flores Le Roux, Juana Antonia, Goday Arnó, Albert
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10230/48649
Acceso en línea:http://hdl.handle.net/10230/48649
http://dx.doi.org/10.3390/jcm9103193
Access Level:acceso abierto
Palabra clave:Bariatric surgery
Gastric bypass
Obesity
Severe obesity
Sleeve gastrectomy
Weight loss
Weight regain
Descripción
Sumario:To ascertain the 5-year metabolic effects of bariatric surgery in poor weight loss (WL) responders and establish associated factors. Methods: Retrospective analysis of a non-randomised prospective cohort of bariatric surgery patients completing a 5-year follow-up. Mid-term poor WL was considered when 5-year excess weight loss was <50%. Results: Forty-three (20.3%) of the 212 included patients were mid-term poor WL responders. They showed an improvement in all metabolic markers at 2 years, except for total cholesterol. This improvement with respect to baseline was maintained at 5 years for plasma glucose, HbA1c, HOMA, HDL and diastolic blood pressure; however, LDL cholesterol, triglycerides and systolic blood pressure were similar to presurgical values. Comorbidity remission rates were comparable to those obtained in the good WL group except for hypercholesterolaemia (45.8% vs. poor WL, p = 0.005). On multivariate analysis, lower baseline HDL cholesterol levels, advanced age and lower preoperative weight loss were independently associated with poor mid-term WL. Conclusions: Although that 1 in 5 patients presented suboptimal WL 5 years after bariatric surgery, other important metabolic benefits were maintained.

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