Longitudinal degeneration of the basal forebrain predicts subsequent dementia in Parkinson's disease

[Objectives] Cholinergic dysfunction plays a prominent role in cognitive impairment in Parkinson's disease (PD). The aim of this study was to assess the relationship of baseline and longitudinal basal forebrain atrophy with cognitive decline and dementia in PD.

Detalles Bibliográficos
Autores: Pereira, Joana B., Hall, Sara, Jalakas, Mattis, Grothe, Michel J., Strandberg, Olof T., Stomrud, Erik, Westman, Eric, van Westen, Danielle, Hansson, Oskar
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/236352
Acceso en línea:http://hdl.handle.net/10261/236352
Access Level:acceso abierto
Palabra clave:Parkinson's disease
Dementia
Basal forebrain
Longitudinal MRI
Cognitive decline
Descripción
Sumario:[Objectives] Cholinergic dysfunction plays a prominent role in cognitive impairment in Parkinson's disease (PD). The aim of this study was to assess the relationship of baseline and longitudinal basal forebrain atrophy with cognitive decline and dementia in PD.

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