Preparation and Double Michael Addition Reactions of a Synthetic Equivalent of Nazarov Reagent

A synthetic equivalent of the Nazarov reagent, the silyl derivative 2, able to undergo base-catalyzed double Michael addition reactions with a,b-unsaturated carbonyl compounds, has been developed. The new reagent satisfactorily reacts with unsaturated indolo[2,3-a]quinolizidine lactams to give penta...

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Detalles Bibliográficos
Autores: Amat Tusón, Mercedes, Arioli, Federica, Pérez Bosch, Maria, Molins i Grau, Elies, Bosch Cartes, Joan
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2013
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/108108
Acceso en línea:https://hdl.handle.net/2445/108108
Access Level:acceso abierto
Palabra clave:Indicadors (Química)
Proves i reactius químics
Lactames
Indicators and test-papers
Chemical tests and reagents
Lactams
Descripción
Sumario:A synthetic equivalent of the Nazarov reagent, the silyl derivative 2, able to undergo base-catalyzed double Michael addition reactions with a,b-unsaturated carbonyl compounds, has been developed. The new reagent satisfactorily reacts with unsaturated indolo[2,3-a]quinolizidine lactams to give pentacyclic yohimbinone-type derivatives.