How effective is proximal fibular osteotomy in redistributing joint pressures? Insights from an HTO comparative in-silico study

Background Knee osteoarthritis (KOA) represents a widespread degenerative condition among adults that significantly affects quality of life. This study aims to elucidate the biomechanical implications of proximal fibular osteotomy (PFO), a proposed cost-effective and straightforward intervention for...

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Autores: Morales Ávalos, Jorge Eduardo|||0000-0001-9551-1644, Morales-Avalos, Rodolfo, Martínez Guajardo, Karla V., Pacheco Garcia, Luis Miguel, Perelli, Simone, Monllau, Joan Carles, Sánchez Egea, Antonio José|||0000-0001-8085-6869, Serrancolí, Gil|||0000-0001-5034-2445
Tipo de recurso: artículo
Fecha de publicación:2024
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/414035
Acceso en línea:https://hdl.handle.net/2117/414035
https://dx.doi.org/10.1186/s13018-024-04807-8
Access Level:acceso abierto
Palabra clave:Osteoarthritis
Knee -- Diseases
Biomechanics
Artrosi
Genolls -- Malalties
Biomecànica
Àrees temàtiques de la UPC::Enginyeria mecànica
Àrees temàtiques de la UPC::Enginyeria biomèdica::Biomecànica
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repository_id_str
spelling How effective is proximal fibular osteotomy in redistributing joint pressures? Insights from an HTO comparative in-silico studyMorales Ávalos, Jorge Eduardo|||0000-0001-9551-1644Morales-Avalos, RodolfoMartínez Guajardo, Karla V.Pacheco Garcia, Luis MiguelPerelli, SimoneMonllau, Joan CarlesSánchez Egea, Antonio José|||0000-0001-8085-6869Serrancolí, Gil|||0000-0001-5034-2445OsteoarthritisKnee -- DiseasesBiomechanicsArtrosiGenolls -- MalaltiesBiomecànicaÀrees temàtiques de la UPC::Enginyeria mecànicaÀrees temàtiques de la UPC::Enginyeria biomèdica::BiomecànicaBackground Knee osteoarthritis (KOA) represents a widespread degenerative condition among adults that significantly affects quality of life. This study aims to elucidate the biomechanical implications of proximal fibular osteotomy (PFO), a proposed cost-effective and straightforward intervention for KOA, comparing its effects against traditional high tibial osteotomy (HTO) through in-silico analysis. Methods Using medical imaging and finite element analysis (FEA), this research quantitatively evaluates the biomechanical outcomes of a simulated PFO procedure in patients with severe medial compartment genu-varum, who have undergone surgical correction with HTO. The study focused on evaluating changes in knee joint contact pressures, stress distribution, and anatomical positioning of the center of pressure (CoP). Three models are generated for each of the five patients investigated in this study, a preoperative original condition model, an in-silico PFO based on the same original condition data, and a reversed-engineered HTO in-silico model. Results The novel contribution of this investigation is the quantitative analysis of the impact of PFO on the biomechanics of the knee joint. The results provide mechanical evidence that PFO can effectively redistribute and homogenize joint stresses, while also repositioning the CoP towards the center of the knee, similar to what is observed post HTO. The findings propose PFO as a potentially viable and simpler alternative to conventional surgical methods for managing severe KOA, specifically in patients with medial compartment genu-varum. Conclusion This research also marks the first application of FEA that may support one of the underlying biomechanical theories of PFO, providing a foundation for future clinical and in-silico studies.This work is supported by the Autonomous University of Nuevo León.Peer ReviewedSpringer20242024-06-0420242024-09-10journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/2117/414035https://dx.doi.org/10.1186/s13018-024-04807-8reponame:UPCommons. Portal del coneixement obert de la UPCinstname:Universitat Politècnica de Catalunya (UPC)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:upcommons.upc.edu:2117/4140352026-05-27T15:37:01Z
dc.title.none.fl_str_mv How effective is proximal fibular osteotomy in redistributing joint pressures? Insights from an HTO comparative in-silico study
title How effective is proximal fibular osteotomy in redistributing joint pressures? Insights from an HTO comparative in-silico study
spellingShingle How effective is proximal fibular osteotomy in redistributing joint pressures? Insights from an HTO comparative in-silico study
Morales Ávalos, Jorge Eduardo|||0000-0001-9551-1644
Osteoarthritis
Knee -- Diseases
Biomechanics
Artrosi
Genolls -- Malalties
Biomecànica
Àrees temàtiques de la UPC::Enginyeria mecànica
Àrees temàtiques de la UPC::Enginyeria biomèdica::Biomecànica
title_short How effective is proximal fibular osteotomy in redistributing joint pressures? Insights from an HTO comparative in-silico study
title_full How effective is proximal fibular osteotomy in redistributing joint pressures? Insights from an HTO comparative in-silico study
title_fullStr How effective is proximal fibular osteotomy in redistributing joint pressures? Insights from an HTO comparative in-silico study
title_full_unstemmed How effective is proximal fibular osteotomy in redistributing joint pressures? Insights from an HTO comparative in-silico study
title_sort How effective is proximal fibular osteotomy in redistributing joint pressures? Insights from an HTO comparative in-silico study
dc.creator.none.fl_str_mv Morales Ávalos, Jorge Eduardo|||0000-0001-9551-1644
Morales-Avalos, Rodolfo
Martínez Guajardo, Karla V.
Pacheco Garcia, Luis Miguel
Perelli, Simone
Monllau, Joan Carles
Sánchez Egea, Antonio José|||0000-0001-8085-6869
Serrancolí, Gil|||0000-0001-5034-2445
author Morales Ávalos, Jorge Eduardo|||0000-0001-9551-1644
author_facet Morales Ávalos, Jorge Eduardo|||0000-0001-9551-1644
Morales-Avalos, Rodolfo
Martínez Guajardo, Karla V.
Pacheco Garcia, Luis Miguel
Perelli, Simone
Monllau, Joan Carles
Sánchez Egea, Antonio José|||0000-0001-8085-6869
Serrancolí, Gil|||0000-0001-5034-2445
author_role author
author2 Morales-Avalos, Rodolfo
Martínez Guajardo, Karla V.
Pacheco Garcia, Luis Miguel
Perelli, Simone
Monllau, Joan Carles
Sánchez Egea, Antonio José|||0000-0001-8085-6869
Serrancolí, Gil|||0000-0001-5034-2445
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Osteoarthritis
Knee -- Diseases
Biomechanics
Artrosi
Genolls -- Malalties
Biomecànica
Àrees temàtiques de la UPC::Enginyeria mecànica
Àrees temàtiques de la UPC::Enginyeria biomèdica::Biomecànica
topic Osteoarthritis
Knee -- Diseases
Biomechanics
Artrosi
Genolls -- Malalties
Biomecànica
Àrees temàtiques de la UPC::Enginyeria mecànica
Àrees temàtiques de la UPC::Enginyeria biomèdica::Biomecànica
description Background Knee osteoarthritis (KOA) represents a widespread degenerative condition among adults that significantly affects quality of life. This study aims to elucidate the biomechanical implications of proximal fibular osteotomy (PFO), a proposed cost-effective and straightforward intervention for KOA, comparing its effects against traditional high tibial osteotomy (HTO) through in-silico analysis. Methods Using medical imaging and finite element analysis (FEA), this research quantitatively evaluates the biomechanical outcomes of a simulated PFO procedure in patients with severe medial compartment genu-varum, who have undergone surgical correction with HTO. The study focused on evaluating changes in knee joint contact pressures, stress distribution, and anatomical positioning of the center of pressure (CoP). Three models are generated for each of the five patients investigated in this study, a preoperative original condition model, an in-silico PFO based on the same original condition data, and a reversed-engineered HTO in-silico model. Results The novel contribution of this investigation is the quantitative analysis of the impact of PFO on the biomechanics of the knee joint. The results provide mechanical evidence that PFO can effectively redistribute and homogenize joint stresses, while also repositioning the CoP towards the center of the knee, similar to what is observed post HTO. The findings propose PFO as a potentially viable and simpler alternative to conventional surgical methods for managing severe KOA, specifically in patients with medial compartment genu-varum. Conclusion This research also marks the first application of FEA that may support one of the underlying biomechanical theories of PFO, providing a foundation for future clinical and in-silico studies.
publishDate 2024
dc.date.none.fl_str_mv 2024
2024-06-04
2024
2024-09-10
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/2117/414035
https://dx.doi.org/10.1186/s13018-024-04807-8
url https://hdl.handle.net/2117/414035
https://dx.doi.org/10.1186/s13018-024-04807-8
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:UPCommons. Portal del coneixement obert de la UPC
instname:Universitat Politècnica de Catalunya (UPC)
instname_str Universitat Politècnica de Catalunya (UPC)
reponame_str UPCommons. Portal del coneixement obert de la UPC
collection UPCommons. Portal del coneixement obert de la UPC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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