Anthocyanin tissue bioavailability in animals: possible implications for human health. A systematic review

Anthocyanins (ACNs) are promising health-enhancing phenolic compounds. We focus on ACN animal tissue bioavailability to provide an evidentiary link between tissue ACNs and their associated health properties. We performed a systematic review of electronic libraries; 279 results were retrieved, and 13...

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Detalles Bibliográficos
Autores: Sandoval-Ramírez, Berner Andrée, Catalán Santos, Úrsula, Fernandez-Castillejo, Sara, Rubió Piqué, Laura, Macià i Puig, Ma Alba, Solà, Rosa
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2018
País:España
Institución:Universitat de Lleida (UdL)
Repositorio:Repositori Obert UdL
OAI Identifier:oai:repositori.udl.cat:10459.1/66470
Acceso en línea:https://doi.org/10.1021/acs.jafc.8b04014
http://hdl.handle.net/10459.1/66470
Access Level:acceso abierto
Palabra clave:Compostos fenòlics
Tissue bioavailability
Animal studies
Antocianines
Descripción
Sumario:Anthocyanins (ACNs) are promising health-enhancing phenolic compounds. We focus on ACN animal tissue bioavailability to provide an evidentiary link between tissue ACNs and their associated health properties. We performed a systematic review of electronic libraries; 279 results were retrieved, and 13 publications met inclusion criteria. Extracted information included animal model employed, administration route, doses, analysis method, and ACN concentration values in tissues. Total ACN concentrations were detected in mice kidney (2.17 × 105 pmol/g), liver (1.73 × 105 pmol/g), heart (3.6 × 103 pmol/g), and lung (1.16 × 105 pmol/g); and in pig brain (6.08 × 103 pmol/g). ACNs showed a predominance of parent ACNs in long-term experiments versus an ACN metabolite predominance in short-term experiments. ACNs detected in animal tissues, such as cyanidin-3-glucoside, suggest it may have an important role in human health. This information could be useful to determine proper ACN-intake biomarkers in biological samples in futures studies.