A significant response to sunitinib in a patient with anaplastic thyroid carcinoma

Anaplastic thyroid cancer (ATC) is a rare disease with an incidence of less than three cases per million of habitants in western countries. ATC accounts for 1-10% of all tumors derived from the thyroid gland. Classic chemotherapy approach based on platinum and anthracyclines regimens have been consi...

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Detalles Bibliográficos
Autores: Grande, Enrique|||0000-0002-0134-4732, Capdevila Castillón, Jaume|||0000-0003-0718-8619, Díez, Juan José|||0000-0002-2017-0694, Longo, Federico|||0000-0003-0902-2188, Carrato, Alfredo|||0000-0001-7749-8140
Tipo de recurso: artículo
Fecha de publicación:2013
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:184999
Acceso en línea:https://ddd.uab.cat/record/184999
Access Level:acceso abierto
Palabra clave:Anaplastic thyroid cancer
Angiogenesis
Sunitinib
Descripción
Sumario:Anaplastic thyroid cancer (ATC) is a rare disease with an incidence of less than three cases per million of habitants in western countries. ATC accounts for 1-10% of all tumors derived from the thyroid gland. Classic chemotherapy approach based on platinum and anthracyclines regimens have been considered standard for the last decades. Novel multitarget agents have shown promising responses; however, no positive randomized clinical trials are available up to now. To our knowledge, the case we are presenting here is the first reported case showing clinical and visual activity using sunitinib as a salvage treatment in an ATC patient who was not fit to receive systemic chemotherapy treatment.