A significant response to sunitinib in a patient with anaplastic thyroid carcinoma

Anaplastic thyroid cancer (ATC) is a rare disease with an incidence of less than three cases per million of habitants in western countries. ATC accounts for 1-10% of all tumors derived from the thyroid gland. Classic chemotherapy approach based on platinum and anthracyclines regimens have been consi...

Full description

Bibliographic Details
Authors: Grande, Enrique|||0000-0002-0134-4732, Capdevila Castillón, Jaume|||0000-0003-0718-8619, Díez, Juan José|||0000-0002-2017-0694, Longo, Federico|||0000-0003-0902-2188, Carrato, Alfredo|||0000-0001-7749-8140
Format: article
Publication Date:2013
Country:España
Institution:Universitat Autònoma de Barcelona
Repository:Dipòsit Digital de Documents de la UAB
Language:English
OAI Identifier:oai:ddd.uab.cat:184999
Online Access:https://ddd.uab.cat/record/184999
Access Level:Open access
Keyword:Anaplastic thyroid cancer
Angiogenesis
Sunitinib
Description
Summary:Anaplastic thyroid cancer (ATC) is a rare disease with an incidence of less than three cases per million of habitants in western countries. ATC accounts for 1-10% of all tumors derived from the thyroid gland. Classic chemotherapy approach based on platinum and anthracyclines regimens have been considered standard for the last decades. Novel multitarget agents have shown promising responses; however, no positive randomized clinical trials are available up to now. To our knowledge, the case we are presenting here is the first reported case showing clinical and visual activity using sunitinib as a salvage treatment in an ATC patient who was not fit to receive systemic chemotherapy treatment.