Antioxidants included in the diet of fattening lambs: Effects on immune response, stress, welfare and distal gut microbiota

9 páginas, 2 figuras, 7 tablas.

Detalhes bibliográficos
Autores: Morán, Lara, Andrés, Sonia, Bodas, Raúl, Benavides, Julio, Prieto, Nuria, Pérez Pérez, Valentín, Giráldez, Francisco Javier
Formato: artículo
Fecha de publicación:2012
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/49685
Acesso em linha:http://hdl.handle.net/10261/49685
Access Level:acceso abierto
Palavra-chave:Carnosic acid
Vitamin E
Immune response
Welfare
Oxidative stress
Gut microbiota
id ES_35e960b61ee8bfb08645976ce2a36a0d
oai_identifier_str oai:digital.csic.es:10261/49685
network_acronym_str ES
network_name_str España
repository_id_str
spelling Antioxidants included in the diet of fattening lambs: Effects on immune response, stress, welfare and distal gut microbiotaMorán, LaraAndrés, SoniaBodas, RaúlBenavides, JulioPrieto, NuriaPérez Pérez, ValentínGiráldez, Francisco JavierCarnosic acidVitamin EImmune responseWelfareOxidative stressGut microbiota9 páginas, 2 figuras, 7 tablas.Thirty-two Merino lambs were fed barley straw plus a concentrate alone (CONTROL) or concentrate enriched with vitamin E (0.6 g/kg of concentrate, VITE006) or with one of two amounts of carnosic acid (0.6 g/kg of concentrate CARN006; 1.2 g/kg of concentrate, CARN012). Effects of these antioxidant compounds on the immune response, stress during road transport, and gut microbiota were assessed. After 7 weeks of being fed the experimental diets, blood samples were taken to measure blood lymphocyte subpopulations by flow cytometry and interferon-gamma (IFN-γ) production; then, all lambs were subjected to a 4-h transportation–stress period to study the evolution of haematological and biological parameters during road transport. Finally, rumen and faeces samples were collected to study microbial diversity. Carnosic acid promoted changes in the faecal bacterial community (P<0.001), whereas vitamin E enhanced IFN-γ production (P<0.05) and reduced tissue damage (creatine phosphokinase, P<0.05) during road transport. Consequently, vitamin E showed some immunological properties and protection against tissue damage during road transport. This may contribute towards improving the welfare of these animals. Changes in the faecal bacterial community promoted by carnosic acid might be related to changes in the chemical composition of the meat. No immunological properties were observed for carnosic acid, and no changes in the feacal or ruminal bacterial communities were observed when vitamine E was supplemented to fattening lambs.Financial support received from ‘Consejería de Educación de la Junta de Castilla y León’ (Project CSI185B11-2) is gratefully acknowledged. Raúl Bodas, Nuria Prieto, Julio Benavides (JAE-Doc contracts) and Lara Morán (JAE pre-doc grant) were supported by the programme ‘Junta para la Ampliación de Estudios’ from CSIC.Peer reviewedElsevier201220122012info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501http://hdl.handle.net/10261/49685reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Ingléshttp://dx.doi.org/10.1016/j.anifeedsci.2012.01.010info:eu-repo/semantics/openAccessoai:digital.csic.es:10261/496852026-05-22T06:33:51Z
dc.title.none.fl_str_mv Antioxidants included in the diet of fattening lambs: Effects on immune response, stress, welfare and distal gut microbiota
title Antioxidants included in the diet of fattening lambs: Effects on immune response, stress, welfare and distal gut microbiota
spellingShingle Antioxidants included in the diet of fattening lambs: Effects on immune response, stress, welfare and distal gut microbiota
Morán, Lara
Carnosic acid
Vitamin E
Immune response
Welfare
Oxidative stress
Gut microbiota
title_short Antioxidants included in the diet of fattening lambs: Effects on immune response, stress, welfare and distal gut microbiota
title_full Antioxidants included in the diet of fattening lambs: Effects on immune response, stress, welfare and distal gut microbiota
title_fullStr Antioxidants included in the diet of fattening lambs: Effects on immune response, stress, welfare and distal gut microbiota
title_full_unstemmed Antioxidants included in the diet of fattening lambs: Effects on immune response, stress, welfare and distal gut microbiota
title_sort Antioxidants included in the diet of fattening lambs: Effects on immune response, stress, welfare and distal gut microbiota
dc.creator.none.fl_str_mv Morán, Lara
Andrés, Sonia
Bodas, Raúl
Benavides, Julio
Prieto, Nuria
Pérez Pérez, Valentín
Giráldez, Francisco Javier
author Morán, Lara
author_facet Morán, Lara
Andrés, Sonia
Bodas, Raúl
Benavides, Julio
Prieto, Nuria
Pérez Pérez, Valentín
Giráldez, Francisco Javier
author_role author
author2 Andrés, Sonia
Bodas, Raúl
Benavides, Julio
Prieto, Nuria
Pérez Pérez, Valentín
Giráldez, Francisco Javier
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Carnosic acid
Vitamin E
Immune response
Welfare
Oxidative stress
Gut microbiota
topic Carnosic acid
Vitamin E
Immune response
Welfare
Oxidative stress
Gut microbiota
description 9 páginas, 2 figuras, 7 tablas.
publishDate 2012
dc.date.none.fl_str_mv 2012
2012
2012
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/49685
url http://hdl.handle.net/10261/49685
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv http://dx.doi.org/10.1016/j.anifeedsci.2012.01.010
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869405924521672704
score 15.812455

Registos relacionados