Sex differences in neuroimmunoendocrine communication. Involvement on longevity

Endocrine, nervous, and immune systems work coordinately to maintain the global homeostasis of the organism. They show sex differences in their functions that, in turn, contribute to sex differences beyond reproductive function. Females display a better control of the energetic metabolism and improv...

Descripción completa

Detalles Bibliográficos
Autores: Suárez González, Luz María, Díaz Del Cerro, Estefanía, Félix, Judith, González Sánchez, Mónica, Ceprián, Noemí, Guerra Pérez, Natalia, Garrido Novelle, Marta, Martínez De Toda Cabeza, Irene, Fuente Del Rey, María Mónica De La
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/88568
Acceso en línea:https://hdl.handle.net/20.500.14352/88568
Access Level:acceso abierto
Palabra clave:612.67
Aging
Gonadal hormones
Immune system
Nervous system
Energetic metabolism
Fisiología
2410.10 Fisiología Humana
2402.15 Envejecimiento Somático
Descripción
Sumario:Endocrine, nervous, and immune systems work coordinately to maintain the global homeostasis of the organism. They show sex differences in their functions that, in turn, contribute to sex differences beyond reproductive function. Females display a better control of the energetic metabolism and improved neuroprotection and have more antioxidant defenses and a better inflammatory status than males, which is associated with a more robust immune response than that of males. These differences are present from the early stages of life, being more relevant in adulthood and influencing the aging trajectory in each sex and may contribute to the different life lifespan between sexes.