Usefulness of the analytical control of aflatoxins in feedstuffs for dairy cows for the prevention of aflatoxin M1 in milk

Aflatoxin M1 (AFM1) is a hydroxylated metabolite of aflatoxin B1 (AFB1) and can be excreted in milk of cows after consuming aflatoxin (AF)-contaminated feed. The aim of this research was to assess the levels of total AFs in samples of feedingstuff for dairy cows (n = 193) and the levels of AFM1 in r...

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Authors: Rodríguez-Blanco, María, Ramos Girona, Antonio J., Prim, M., Sanchís Almenar, Vicente, Marín Sillué, Sònia
Format: article
Status:Versión aceptada para publicación
Publication Date:2019
Country:España
Institution:Universitat de Lleida (UdL)
Repository:Repositori Obert UdL
OAI Identifier:oai:repositori.udl.cat:10459.1/68009
Online Access:https://doi.org/10.1007/s12550-019-00362-y
http://hdl.handle.net/10459.1/68009
Access Level:Open access
Keyword:Aflatoxin M1
Aflatoxin transfer ratio
Total mixed ration
Raw bulk milk
Aflatoxin B1
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spelling Usefulness of the analytical control of aflatoxins in feedstuffs for dairy cows for the prevention of aflatoxin M1 in milkRodríguez-Blanco, MaríaRamos Girona, Antonio J.Prim, M.Sanchís Almenar, VicenteMarín Sillué, SòniaAflatoxin M1Aflatoxin transfer ratioTotal mixed rationRaw bulk milkAflatoxin B1Aflatoxin M1 (AFM1) is a hydroxylated metabolite of aflatoxin B1 (AFB1) and can be excreted in milk of cows after consuming aflatoxin (AF)-contaminated feed. The aim of this research was to assess the levels of total AFs in samples of feedingstuff for dairy cows (n = 193) and the levels of AFM1 in raw bulk tank milk samples (n = 375), in order to estimate the ratio of BAFB1 feed input^ versus BAFM1 milk output^ in four specific regions of Spain. Moreover, the correlation between the raw materials used as ingredients of the total mixed ration (TMR) and the presence of AFs was studied. About one-third (34.7%) of the feed samples were positive for total AFs in a range of 0.05-6.45 μg/kg, and 12.4% were positive for AFB1. AFM1 was detected in 18.9% of bulk milk samples, with concentrations ranging from 0.009 to 1.36 μg/kg. While none of the feed samples exceeded the European Union (EU) maximumcontent for AFB1 in feedingstuff for dairy animals of 5 μg/kg, three bulk milk samples exceeded the EU maximum level for AFM1 in milk of 50 ng/kg. The transfer ratio AFB1/AFM1, which was derived from AFB1 levels in feed, AFM1 levels in bulk tank milk, feed intake, and milk yield data, was 0.6-6%, which corresponded well with the range of published carry-over data for aflatoxins. Statistical analyses showed that the main sources of AFB1 in TMR were maize silage, bagasse, soya bean husk, maize, alfalfa hay, cotton seed and compound feed, thus special attention should be paid in controlling these raw materials when used in TMR preparation. Although the analysis of AFs in feed did not correlate with the presence of AFM1 in milk, monitoring feedstuffs is a useful tool in order to try and minimise AF-contamination of milk.This work was supported by the Spanish Ministry of Economy and Competitiveness (project AGL2014-55379-P). M. Rodríguez-Blanco thanks the University of Lleida for a pre-doctoral grant.Springer Nature2019info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionapplication/pdfhttps://doi.org/10.1007/s12550-019-00362-yhttp://hdl.handle.net/10459.1/68009reponame:Repositori Obert UdL instname:Universitat de Lleida (UdL)Inglésinfo:eu-repo/grantAgreement/MINECO//AGL2014-55379-PVersió postprint del document publicat a: https://doi.org/10.1007/s12550-019-00362-yMycotoxin Research, 2019, vol. 36, num. 1, p. 11-22(c) Society for Mycotoxin (Research Gesellschaft für Mykotoxinforschung e.V.) and Springer-Verlag GmbH Germany, part of Springer Nature, 2019info:eu-repo/semantics/openAccessoai:repositori.udl.cat:10459.1/680092026-06-24T12:42:17Z
dc.title.none.fl_str_mv Usefulness of the analytical control of aflatoxins in feedstuffs for dairy cows for the prevention of aflatoxin M1 in milk
title Usefulness of the analytical control of aflatoxins in feedstuffs for dairy cows for the prevention of aflatoxin M1 in milk
spellingShingle Usefulness of the analytical control of aflatoxins in feedstuffs for dairy cows for the prevention of aflatoxin M1 in milk
Rodríguez-Blanco, María
Aflatoxin M1
Aflatoxin transfer ratio
Total mixed ration
Raw bulk milk
Aflatoxin B1
title_short Usefulness of the analytical control of aflatoxins in feedstuffs for dairy cows for the prevention of aflatoxin M1 in milk
title_full Usefulness of the analytical control of aflatoxins in feedstuffs for dairy cows for the prevention of aflatoxin M1 in milk
title_fullStr Usefulness of the analytical control of aflatoxins in feedstuffs for dairy cows for the prevention of aflatoxin M1 in milk
title_full_unstemmed Usefulness of the analytical control of aflatoxins in feedstuffs for dairy cows for the prevention of aflatoxin M1 in milk
title_sort Usefulness of the analytical control of aflatoxins in feedstuffs for dairy cows for the prevention of aflatoxin M1 in milk
dc.creator.none.fl_str_mv Rodríguez-Blanco, María
Ramos Girona, Antonio J.
Prim, M.
Sanchís Almenar, Vicente
Marín Sillué, Sònia
author Rodríguez-Blanco, María
author_facet Rodríguez-Blanco, María
Ramos Girona, Antonio J.
Prim, M.
Sanchís Almenar, Vicente
Marín Sillué, Sònia
author_role author
author2 Ramos Girona, Antonio J.
Prim, M.
Sanchís Almenar, Vicente
Marín Sillué, Sònia
author2_role author
author
author
author
dc.subject.none.fl_str_mv Aflatoxin M1
Aflatoxin transfer ratio
Total mixed ration
Raw bulk milk
Aflatoxin B1
topic Aflatoxin M1
Aflatoxin transfer ratio
Total mixed ration
Raw bulk milk
Aflatoxin B1
description Aflatoxin M1 (AFM1) is a hydroxylated metabolite of aflatoxin B1 (AFB1) and can be excreted in milk of cows after consuming aflatoxin (AF)-contaminated feed. The aim of this research was to assess the levels of total AFs in samples of feedingstuff for dairy cows (n = 193) and the levels of AFM1 in raw bulk tank milk samples (n = 375), in order to estimate the ratio of BAFB1 feed input^ versus BAFM1 milk output^ in four specific regions of Spain. Moreover, the correlation between the raw materials used as ingredients of the total mixed ration (TMR) and the presence of AFs was studied. About one-third (34.7%) of the feed samples were positive for total AFs in a range of 0.05-6.45 μg/kg, and 12.4% were positive for AFB1. AFM1 was detected in 18.9% of bulk milk samples, with concentrations ranging from 0.009 to 1.36 μg/kg. While none of the feed samples exceeded the European Union (EU) maximumcontent for AFB1 in feedingstuff for dairy animals of 5 μg/kg, three bulk milk samples exceeded the EU maximum level for AFM1 in milk of 50 ng/kg. The transfer ratio AFB1/AFM1, which was derived from AFB1 levels in feed, AFM1 levels in bulk tank milk, feed intake, and milk yield data, was 0.6-6%, which corresponded well with the range of published carry-over data for aflatoxins. Statistical analyses showed that the main sources of AFB1 in TMR were maize silage, bagasse, soya bean husk, maize, alfalfa hay, cotton seed and compound feed, thus special attention should be paid in controlling these raw materials when used in TMR preparation. Although the analysis of AFs in feed did not correlate with the presence of AFM1 in milk, monitoring feedstuffs is a useful tool in order to try and minimise AF-contamination of milk.
publishDate 2019
dc.date.none.fl_str_mv 2019
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://doi.org/10.1007/s12550-019-00362-y
http://hdl.handle.net/10459.1/68009
url https://doi.org/10.1007/s12550-019-00362-y
http://hdl.handle.net/10459.1/68009
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv info:eu-repo/grantAgreement/MINECO//AGL2014-55379-P
Versió postprint del document publicat a: https://doi.org/10.1007/s12550-019-00362-y
Mycotoxin Research, 2019, vol. 36, num. 1, p. 11-22
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer Nature
publisher.none.fl_str_mv Springer Nature
dc.source.none.fl_str_mv reponame:Repositori Obert UdL
instname:Universitat de Lleida (UdL)
instname_str Universitat de Lleida (UdL)
reponame_str Repositori Obert UdL
collection Repositori Obert UdL
repository.name.fl_str_mv
repository.mail.fl_str_mv
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