Tracing illicit and prescription drug use in a Spanish prison by combining wastewater analysis and pharmaceutical dispensing data

Background and aim We combined wastewater-based epidemiology (WBE) and pharmaceutical dispensing records to distinguish between illicit and prescription drug use. Methods We collected 24-h composite wastewater samples during three one-week campaigns in a prison in northern Spain. Samples were analys...

Descripción completa

Detalles Bibliográficos
Autores: Egaña, Iker, Nogales-García, Maite, Akhrimenko, Vladimir, González Gómez, Xiana, Rodil Rodríguez, María del Rosario, Montes Goyanes, Rosa, Quintana Álvarez, José Benito, Mestre-Pintó, Juan Ignacio, Orive, Gorka, Lertxundi, Unax
Tipo de recurso: artículo
Fecha de publicación:2026
País:España
Institución:Universidad de Santiago de Compostela (USC)
Repositorio:Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Idioma:inglés
OAI Identifier:oai:dnet:minerva_____::5a51642272863e5dfdb20297154472e7
Acceso en línea:https://hdl.handle.net/10347/46828
Access Level:acceso abierto
Palabra clave:Wastewater based epidemiology
Drugs & prison
Drug trafficking
Gabapentinoids
Illicit drugs
Alcohol
Descripción
Sumario:Background and aim We combined wastewater-based epidemiology (WBE) and pharmaceutical dispensing records to distinguish between illicit and prescription drug use. Methods We collected 24-h composite wastewater samples during three one-week campaigns in a prison in northern Spain. Samples were analysed for pharmaceuticals, illicit drugs, nicotine and alcohol. Population-normalised daily loads (PNDLs) were converted to consumption estimates and compared with Spanish population WBE estimates and pharmacy dispensing data. Results Wastewater analysis showed high use of several pharmaceuticals, with the highest average PNDL for gabapentinoids. Pregabalin and gabapentin estimates from wastewater exceeded pharmacy dispensing, suggesting internal diversion. Cannabis consumption was about four times higher than community estimates and cocaine was also higher in all campaigns. Ketamine and MDMA use were above community medians during the February campaign and nicotine use was nearly ten times higher than community levels. Conclusion WBE identifies prescription drug diversion, illicit drug markets and quantifies licit substance use in prisons.