Identification of atrial-enriched lncRNA Walras linked to cardiomyocyte cytoarchitecture and atrial fibrillation

Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia in humans. Genetic and genomic analyses have recently demonstrated that the homeobox transcription factor Pitx2 plays a fundamental role regulating expression of distinct growth factors, microRNAs and ion channels leading to morpholog...

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Autores: García-Padilla, Carlos, Domínguez, Jorge N., Lodde, Valeria, Munk, Rachel, Abdelmohsen, Kotb, Gorospe, Myriam, Jiménez-Sábado, Verónica|||0000-0001-7720-988X, Ginel, Antonino|||0000-0002-8820-7545, Madsen, Leif Hove|||0000-0001-5493-3998, Aránega, Amelia|||0000-0002-0046-9410, Franco, Diego|||0000-0002-5669-7164
Tipo de recurso: artículo
Fecha de publicación:2022
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:280902
Acceso en línea:https://ddd.uab.cat/record/280902
https://dx.doi.org/urn:doi:10.1096/fj.202100844RR
Access Level:acceso abierto
Palabra clave:Animals
Atrial Fibrillation
Cytoskeleton
Heart Atria
Humans
Lncrna
Mice
Mice, Knockout
Myocytes, Cardiac
Post-transcriptional regulation
RNA, Long Noncoding
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oai_identifier_str oai:ddd.uab.cat:280902
network_acronym_str ES
network_name_str España
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spelling Identification of atrial-enriched lncRNA Walras linked to cardiomyocyte cytoarchitecture and atrial fibrillationGarcía-Padilla, CarlosDomínguez, Jorge N.Lodde, ValeriaMunk, RachelAbdelmohsen, KotbGorospe, MyriamJiménez-Sábado, Verónica|||0000-0001-7720-988XGinel, Antonino|||0000-0002-8820-7545Madsen, Leif Hove|||0000-0001-5493-3998Aránega, Amelia|||0000-0002-0046-9410Franco, Diego|||0000-0002-5669-7164AnimalsAtrial FibrillationCytoskeletonHeart AtriaHumansLncrnaMiceMice, KnockoutMyocytes, CardiacPost-transcriptional regulationRNA, Long NoncodingAtrial fibrillation (AF) is the most prevalent cardiac arrhythmia in humans. Genetic and genomic analyses have recently demonstrated that the homeobox transcription factor Pitx2 plays a fundamental role regulating expression of distinct growth factors, microRNAs and ion channels leading to morphological and molecular alterations that promote the onset of AF. Here we address the plausible contribution of long non-coding (lnc)RNAs within the Pitx2. 22022-01-0120222022-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/280902https://dx.doi.org/urn:doi:10.1096/fj.202100844RRreponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengMinisterio de Ciencia, Innovación y Universidades https://doi.org/10.13039/100014440 BFU2015-67131Popen accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.https://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:2809022026-06-06T12:50:31Z
dc.title.none.fl_str_mv Identification of atrial-enriched lncRNA Walras linked to cardiomyocyte cytoarchitecture and atrial fibrillation
title Identification of atrial-enriched lncRNA Walras linked to cardiomyocyte cytoarchitecture and atrial fibrillation
spellingShingle Identification of atrial-enriched lncRNA Walras linked to cardiomyocyte cytoarchitecture and atrial fibrillation
García-Padilla, Carlos
Animals
Atrial Fibrillation
Cytoskeleton
Heart Atria
Humans
Lncrna
Mice
Mice, Knockout
Myocytes, Cardiac
Post-transcriptional regulation
RNA, Long Noncoding
title_short Identification of atrial-enriched lncRNA Walras linked to cardiomyocyte cytoarchitecture and atrial fibrillation
title_full Identification of atrial-enriched lncRNA Walras linked to cardiomyocyte cytoarchitecture and atrial fibrillation
title_fullStr Identification of atrial-enriched lncRNA Walras linked to cardiomyocyte cytoarchitecture and atrial fibrillation
title_full_unstemmed Identification of atrial-enriched lncRNA Walras linked to cardiomyocyte cytoarchitecture and atrial fibrillation
title_sort Identification of atrial-enriched lncRNA Walras linked to cardiomyocyte cytoarchitecture and atrial fibrillation
dc.creator.none.fl_str_mv García-Padilla, Carlos
Domínguez, Jorge N.
Lodde, Valeria
Munk, Rachel
Abdelmohsen, Kotb
Gorospe, Myriam
Jiménez-Sábado, Verónica|||0000-0001-7720-988X
Ginel, Antonino|||0000-0002-8820-7545
Madsen, Leif Hove|||0000-0001-5493-3998
Aránega, Amelia|||0000-0002-0046-9410
Franco, Diego|||0000-0002-5669-7164
author García-Padilla, Carlos
author_facet García-Padilla, Carlos
Domínguez, Jorge N.
Lodde, Valeria
Munk, Rachel
Abdelmohsen, Kotb
Gorospe, Myriam
Jiménez-Sábado, Verónica|||0000-0001-7720-988X
Ginel, Antonino|||0000-0002-8820-7545
Madsen, Leif Hove|||0000-0001-5493-3998
Aránega, Amelia|||0000-0002-0046-9410
Franco, Diego|||0000-0002-5669-7164
author_role author
author2 Domínguez, Jorge N.
Lodde, Valeria
Munk, Rachel
Abdelmohsen, Kotb
Gorospe, Myriam
Jiménez-Sábado, Verónica|||0000-0001-7720-988X
Ginel, Antonino|||0000-0002-8820-7545
Madsen, Leif Hove|||0000-0001-5493-3998
Aránega, Amelia|||0000-0002-0046-9410
Franco, Diego|||0000-0002-5669-7164
author2_role author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Animals
Atrial Fibrillation
Cytoskeleton
Heart Atria
Humans
Lncrna
Mice
Mice, Knockout
Myocytes, Cardiac
Post-transcriptional regulation
RNA, Long Noncoding
topic Animals
Atrial Fibrillation
Cytoskeleton
Heart Atria
Humans
Lncrna
Mice
Mice, Knockout
Myocytes, Cardiac
Post-transcriptional regulation
RNA, Long Noncoding
description Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia in humans. Genetic and genomic analyses have recently demonstrated that the homeobox transcription factor Pitx2 plays a fundamental role regulating expression of distinct growth factors, microRNAs and ion channels leading to morphological and molecular alterations that promote the onset of AF. Here we address the plausible contribution of long non-coding (lnc)RNAs within the Pitx2.
publishDate 2022
dc.date.none.fl_str_mv 2
2022-01-01
2022
2022-01-01
dc.type.none.fl_str_mv Article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://ddd.uab.cat/record/280902
https://dx.doi.org/urn:doi:10.1096/fj.202100844RR
url https://ddd.uab.cat/record/280902
https://dx.doi.org/urn:doi:10.1096/fj.202100844RR
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv Ministerio de Ciencia, Innovación y Universidades https://doi.org/10.13039/100014440 BFU2015-67131P
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by-nc/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by-nc/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Dipòsit Digital de Documents de la UAB
instname:Universitat Autònoma de Barcelona
instname_str Universitat Autònoma de Barcelona
reponame_str Dipòsit Digital de Documents de la UAB
collection Dipòsit Digital de Documents de la UAB
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,300724

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