Mid-trimester uterine artery Doppler for aspirin discontinuation in pregnancies at high risk for preterm pre-eclampsia

Objective: To assess whether aspirin treatment can be discontinued in pregnancies with normal uterine artery pulsatility index (≤90th percentile) at 24-28 weeks. Design: Post-hoc analysis of a clinical trial. Setting: Nine maternity hospitals in Spain. Population or Sample: Pregnant individuals at h...

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Detalles Bibliográficos
Autores: Bonacina, Erika|||0000-0002-8042-8247, García Manau, Pablo|||0000-0002-2415-1626, López Rodríguez, Mónica, Caamiña Álvarez, Sara|||0000-0001-9178-3132, Vives, Àngels|||0000-0001-9712-6379, Lopez-Quesada, Eva|||0000-0002-4477-3246, Ricart, Marta|||0000-0003-0099-6525, Maroto, Anna|||0000-0003-3225-9095, de Mingo, Laura, Pintado, Elena, Castillo-Ribelles, Laura|||0000-0001-9380-7839, Martin, Lourdes|||0000-0003-1781-5305, Rodriguez-Zurita, Alicia|||0000-0003-4177-4726, Garcia Cancela, Esperanza|||0000-0001-8924-9096, Pallarols, Mar, Vidal-Sagnier, Laia, Teixidor, Mireia|||0000-0001-8548-1648, Orizales Lago, Carmen María|||0000-0001-7184-2799, Pérez-Gomez, Adela, Ocaña, Vanesa|||0000-0003-2547-5646, Puerto Tamayo, Linda Grace|||0000-0001-5539-6397, Millán, Pilar, Alsius, Mercè, Díaz Rodríguez, Sonia|||0000-0001-6689-1895, Maiz, Nerea|||0000-0001-8261-6383, Carreras Moratonas, Elena|||0000-0003-3471-7248, Suy, Anna|||0000-0003-2987-6105, Mendoza, Manel|||0000-0002-3030-3833
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:283528
Acceso en línea:https://ddd.uab.cat/record/283528
https://dx.doi.org/urn:doi:10.1111/1471-0528.17631
Access Level:acceso abierto
Palabra clave:Aspirin
Doppler
Pre-eclampsia
Salicylic acid
Screening
Uterine artery
Descripción
Sumario:Objective: To assess whether aspirin treatment can be discontinued in pregnancies with normal uterine artery pulsatility index (≤90th percentile) at 24-28 weeks. Design: Post-hoc analysis of a clinical trial. Setting: Nine maternity hospitals in Spain. Population or Sample: Pregnant individuals at high risk of pre-eclampsia at 11-13 weeks and normal uterine artery Doppler at 24-28 weeks. Methods: All participants received treatment with daily aspirin at a dose of 150 mg. Participants were randomly assigned, in a 1:1 ratio, either to continue aspirin treatment until 36 weeks (control group) or to discontinue aspirin treatment (intervention group), between September 2019 and September 2021. In this secondary analysis, women with a UtAPI.

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