Validation of the 'Test of the Adherence to Inhalers' (TAI) for Asthma and COPD Patients

Background: To validate the Test of Adherence to Inhalers' (TAI), a 12-item questionnaire designed to assess the adherence to inhalers in patients with COPD or asthma. Methods: A total of 1009 patients with asthma or COPD participated in a cross-sectional multicenter study. Patients with electr...

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Detalles Bibliográficos
Autores: Plaza, Vicente, Fernández-Rodríguez, Concepción, Melero, Carlos, García-Cosío, Borja, Manuel Entrenas, Luis, Perez de Llano, Luis Alejandro, Gutierrez-Pereyra, Fernando, Tarragona, Eduard, Palomino, Rosa, Lopez-Vina, Antolin, TAI Study Grp
Tipo de recurso: artículo
Fecha de publicación:2016
País:España
Institución:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/20239
Acceso en línea:http://hdl.handle.net/20.500.12105/20239
Access Level:acceso abierto
Palabra clave:Anti-asthmatic agents
Administration and dosage
Inhalers
Medication adherence
Medication non-adherence
Questionnaires
Pulmonary disease
Chronic obstructive
Drug therapy
Validation studies
Reproducibilidad de los Resultados
Femenino
Pulmón
Administración por Inhalación
Masculino
Nebulizadores y Vaporizadores
Cumplimiento de la Medicación
Estudios Transversales
Enfermedad Pulmonar Obstructiva Crónica
Broncodilatadores
Proyectos Piloto
Humanos
Persona de Mediana Edad
Conocimientos, Actitudes y Práctica en Salud
Anciano
Asma
Encuestas y Cuestionarios
Adulto
Psicometría
España
Área Bajo la Curva
Curva ROC
Area Under Curve
Asthma
Aged
Spain
Adult
Pulmonary Disease, Chronic Obstructive
Humans
Health Knowledge, Attitudes, Practice
Bronchodilator Agents
Middle Aged
Cross-Sectional Studies
Lung
Male
Descripción
Sumario:Background: To validate the Test of Adherence to Inhalers' (TAI), a 12-item questionnaire designed to assess the adherence to inhalers in patients with COPD or asthma. Methods: A total of 1009 patients with asthma or COPD participated in a cross-sectional multicenter study. Patients with electronic adherence 80% were defined as adherents. Construct validity, internal validity, and criterion validity were evaluated. Self-reported adherence was compared with the Morisky-Green questionnaire. Results: Factor analysis study demonstrated two factors, factor 1 was coincident with TAI patient domain (items 1 to 10) and factor 2 with TAI health-care professional domain (items 11 and 12). The Cronbach's alpha was 0.860 and the test-retest reliability 0.883. TAI scores correlated with electronic adherence (=0.293, p=0.01). According to the best cut-off for 10 items (score 50, area under the ROC curve 0.7), 569 (62.5%) patients were classified as non-adherents. The non-adherence behavior pattern was: erratic 527 (57.9%), deliberate 375 (41.2%), and unwitting 242 (26.6%) patients. As compared to Morisky-Green test, TAI showed better psychometric properties. Conclusions: The TAI is a reliable and homogeneous questionnaire to identify easily non-adherence and to classify from a clinical perspective the barriers related to the use of inhalers in asthma and COPD.