Validation of the 'Test of the Adherence to Inhalers' (TAI) for Asthma and COPD Patients

Background: To validate the 'Test of Adherence to Inhalers' (TAI), a 12-item questionnaire designed to assess the adherence to inhalers in patients with COPD or asthma. Methods: A total of 1009 patients with asthma or COPD participated in a cross-sectional multicenter study. Patients with...

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Detalles Bibliográficos
Autores: Plaza, Vicente|||0000-0003-2567-5496, Fernández-Rodríguez, Concepción, Melero, Carlos|||0000-0003-2141-1004, Cosio, Borja G.|||0000-0002-6388-8209, Entrenas Costa, Luis M.|||0000-0003-0664-5531, Pérez de Llano, Luis|||0000-0003-2652-6847, Gutiérrez-Pereyra, Fernando|||0000-0002-6202-4636, Tarragona, Eduard, Palomino, Rosa, López Viña, Antolín|||0000-0001-8057-6947
Tipo de recurso: artículo
Fecha de publicación:2016
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:185387
Acceso en línea:https://ddd.uab.cat/record/185387
https://dx.doi.org/urn:doi:10.1089/jamp.2015.1212
Access Level:acceso abierto
Palabra clave:Anti-asthmatic agents, administration and dosage
Inhalers
Medication adherence
Medication non-adherence
Questionnaires
Pulmonary disease, chronic obstructive, drug therapy
Validation studies
Descripción
Sumario:Background: To validate the 'Test of Adherence to Inhalers' (TAI), a 12-item questionnaire designed to assess the adherence to inhalers in patients with COPD or asthma. Methods: A total of 1009 patients with asthma or COPD participated in a cross-sectional multicenter study. Patients with electronic adherence ≥80% were defined as adherents. Construct validity, internal validity, and criterion validity were evaluated. Self-reported adherence was compared with the Morisky-Green questionnaire. Results: Factor analysis study demonstrated two factors, factor 1 was coincident with TAI patient domain (items 1 to 10) and factor 2 with TAI health-care professional domain (items 11 and 12). The Cronbach's alpha was 0.860 and the test-retest reliability 0.883. TAI scores correlated with electronic adherence (ρ=0.293, p =0.01). According to the best cut-off for 10 items (score 50, area under the ROC curve 0.7), 569 (62.5%) patients were classified as non-adherents. The non-adherence behavior pattern was: erratic 527 (57.9%), deliberate 375 (41.2%), and unwitting 242 (26.6%) patients. As compared to Morisky-Green test, TAI showed better psychometric properties. Conclusions: The TAI is a reliable and homogeneous questionnaire to identify easily non-adherence and to classify from a clinical perspective the barriers related to the use of inhalers in asthma and COPD.

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