ALWAYS ICSI? A SWOT analysis

Purpose: Intracytroplasmatic sperm injection (ICSI) is a common procedure used to improve reproductive results, even among couples without male factor infertility. However, the evidence available is still uncertain on the possible advantages and deficiencies that this procedure may have in patients...

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Autores: Bosch, Ernesto, Espinós, Juan José|||0000-0003-4838-8940, Fabregues, Francisco, Fontes, J, García-Velasco, Juan A.|||0000-0003-1005-8727, Llácer, Joaquín, Requena, Antonio, Checa, Miguel Angel|||0000-0002-0226-3416, Bellver, José
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:318341
Acceso en línea:https://ddd.uab.cat/record/318341
https://dx.doi.org/urn:doi:10.1007/s10815-020-01836-0
Access Level:acceso abierto
Palabra clave:Assisted reproduction
In vitro fertilization (IVF)
Infertility
Intracytoplasmic sperm injection (ICSI)
Pregnancy
Severe non-male factor
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spelling ALWAYS ICSI? A SWOT analysisBosch, ErnestoEspinós, Juan José|||0000-0003-4838-8940Fabregues, FranciscoFontes, JGarcía-Velasco, Juan A.|||0000-0003-1005-8727Llácer, JoaquínRequena, AntonioCheca, Miguel Angel|||0000-0002-0226-3416Bellver, JoséAssisted reproductionIn vitro fertilization (IVF)InfertilityIntracytoplasmic sperm injection (ICSI)PregnancySevere non-male factorPurpose: Intracytroplasmatic sperm injection (ICSI) is a common procedure used to improve reproductive results, even among couples without male factor infertility. However, the evidence available is still uncertain on the possible advantages and deficiencies that this procedure may have in patients with no formal indication for ICSI. Methods: A SWOT (strengths, weaknesses, opportunities, threats) analysis examines the possible advantages and deficiencies of performing ICSI in these patients with no formal indication. Results: The evidence suggests that ICSI is not justified for non-male factor infertile couples requiring in vitro conception. One of the major strengths associated to the procedure is the virtual elimination of cases further complicated by total fertilization failure and a combination between IVF and ICSI on sibling oocytes has been advised in the literature. Greater technical difficulties, higher costs and performing an unnecessary invasive technique in some cases represent some of the weaknesses of the procedure, and questions regarding safety issues should not be ruled out. Conclusion: Despite the widespread use of ICSI in patients without a formal diagnosis of male factor infertility, evidence demonstrating its effectiveness in this population is still lacking. Additional large and well-designed randomized controlled trials are needed to clarify definitive indications for ICSI in non-male factor infertility. 22020-01-0120202020-01-01Articlehttp://purl.org/coar/resource_type/c_6501SMURhttp://purl.org/coar/version/c_71e4c1898caa6e32info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/318341https://dx.doi.org/urn:doi:10.1007/s10815-020-01836-0reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Aquest material està protegit per drets d'autor i/o drets afins. Podeu utilitzar aquest material en funció del que permet la legislació de drets d'autor i drets afins d'aplicació al vostre cas. Per a d'altres usos heu d'obtenir permís del(s) titular(s) de drets.https://rightsstatements.org/vocab/InC/1.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:3183412026-06-06T12:50:31Z
dc.title.none.fl_str_mv ALWAYS ICSI? A SWOT analysis
title ALWAYS ICSI? A SWOT analysis
spellingShingle ALWAYS ICSI? A SWOT analysis
Bosch, Ernesto
Assisted reproduction
In vitro fertilization (IVF)
Infertility
Intracytoplasmic sperm injection (ICSI)
Pregnancy
Severe non-male factor
title_short ALWAYS ICSI? A SWOT analysis
title_full ALWAYS ICSI? A SWOT analysis
title_fullStr ALWAYS ICSI? A SWOT analysis
title_full_unstemmed ALWAYS ICSI? A SWOT analysis
title_sort ALWAYS ICSI? A SWOT analysis
dc.creator.none.fl_str_mv Bosch, Ernesto
Espinós, Juan José|||0000-0003-4838-8940
Fabregues, Francisco
Fontes, J
García-Velasco, Juan A.|||0000-0003-1005-8727
Llácer, Joaquín
Requena, Antonio
Checa, Miguel Angel|||0000-0002-0226-3416
Bellver, José
author Bosch, Ernesto
author_facet Bosch, Ernesto
Espinós, Juan José|||0000-0003-4838-8940
Fabregues, Francisco
Fontes, J
García-Velasco, Juan A.|||0000-0003-1005-8727
Llácer, Joaquín
Requena, Antonio
Checa, Miguel Angel|||0000-0002-0226-3416
Bellver, José
author_role author
author2 Espinós, Juan José|||0000-0003-4838-8940
Fabregues, Francisco
Fontes, J
García-Velasco, Juan A.|||0000-0003-1005-8727
Llácer, Joaquín
Requena, Antonio
Checa, Miguel Angel|||0000-0002-0226-3416
Bellver, José
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Assisted reproduction
In vitro fertilization (IVF)
Infertility
Intracytoplasmic sperm injection (ICSI)
Pregnancy
Severe non-male factor
topic Assisted reproduction
In vitro fertilization (IVF)
Infertility
Intracytoplasmic sperm injection (ICSI)
Pregnancy
Severe non-male factor
description Purpose: Intracytroplasmatic sperm injection (ICSI) is a common procedure used to improve reproductive results, even among couples without male factor infertility. However, the evidence available is still uncertain on the possible advantages and deficiencies that this procedure may have in patients with no formal indication for ICSI. Methods: A SWOT (strengths, weaknesses, opportunities, threats) analysis examines the possible advantages and deficiencies of performing ICSI in these patients with no formal indication. Results: The evidence suggests that ICSI is not justified for non-male factor infertile couples requiring in vitro conception. One of the major strengths associated to the procedure is the virtual elimination of cases further complicated by total fertilization failure and a combination between IVF and ICSI on sibling oocytes has been advised in the literature. Greater technical difficulties, higher costs and performing an unnecessary invasive technique in some cases represent some of the weaknesses of the procedure, and questions regarding safety issues should not be ruled out. Conclusion: Despite the widespread use of ICSI in patients without a formal diagnosis of male factor infertility, evidence demonstrating its effectiveness in this population is still lacking. Additional large and well-designed randomized controlled trials are needed to clarify definitive indications for ICSI in non-male factor infertility.
publishDate 2020
dc.date.none.fl_str_mv 2
2020-01-01
2020
2020-01-01
dc.type.none.fl_str_mv Article
http://purl.org/coar/resource_type/c_6501
SMUR
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dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://ddd.uab.cat/record/318341
https://dx.doi.org/urn:doi:10.1007/s10815-020-01836-0
url https://ddd.uab.cat/record/318341
https://dx.doi.org/urn:doi:10.1007/s10815-020-01836-0
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://rightsstatements.org/vocab/InC/1.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://rightsstatements.org/vocab/InC/1.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Dipòsit Digital de Documents de la UAB
instname:Universitat Autònoma de Barcelona
instname_str Universitat Autònoma de Barcelona
reponame_str Dipòsit Digital de Documents de la UAB
collection Dipòsit Digital de Documents de la UAB
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